DNA double-strand breaks arise accidentally upon exposure of DNA to radiation and
chemicals or result from faulty DNA metabolic processes. DNA breaks can also be …

In flowering plants, male reproductive development requires the formation of the stamen,
including the differentiation of anther tissues. Within the anther, male meiosis produces …

Meiotic crossovers (COs) have intriguing patterning properties, including CO interference,
the tendency of COs to be well-spaced along chromosomes, and heterochiasmy, the marked …

The synaptonemal complex is a tripartite proteinaceous ultrastructure that forms between
homologous chromosomes during prophase I of meiosis in the majority of eukaryotes. It is …

Meiotic recombination proceeds via binding of RPA, RAD51, and DMC1 to single-stranded
DNA (ssDNA) substrates created after formation of programmed DNA double-strand breaks …

Meiotic recombination has a central role in the evolution of sexually reproducing organisms.
The two recombination outcomes, crossover and non-crossover, increase genetic diversity …

Meiotic recombination is carried out through a specialized pathway for the formation and
repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal …

Crossing-over ensures accurate chromosome segregation during meiosis, and every pair of
chromosomes obtains at least one crossover, even though the majority of recombination …

Crossovers produced by homologous recombination promote accurate chromosome
segregation in meiosis and are controlled such that at least one forms per chromosome pair …

The BLM helicase has been shown to maintain genome stability by preventing accumulation
of aberrant recombination intermediates. We show here that the Saccharomyces cerevisiae …