The fundamental functions of epithelia and endothelia in multicellular organisms are to
separate compositionally distinct compartments and regulate the exchange of small solutes …

Background Abnormal endometrial receptivity is one of the major causes of embryo
implantation failure and infertility. The plasma membrane transformation (PMT) describes …

Leukaemia inhibitory factor (LIF) is one of the most important cytokines in the reproductive
tract. Without expression of LIF in the uterus, implantation of a blastocyst cannot begin. Yet …

The tight junctions (TJs) of epithelia are responsible for regulating the “fence and gate”
function of polarized epithelial cells. It is now well-established that dysregulation of these …

Embryo implantation into the receptive endometrium is critical in pregnancy establishment,
initially requiring reciprocal signalling between outer layer of the blastocyst (trophectoderm …

Unavoidable damage to the basal layer of the endometrium has a huge negative impact on
a woman's reproductive health and menstrual cycle. However, it is difficult for medicine to …

Leukemia inhibitory factor plays a major role in the uterus and in its absence embryos fail to
implant. Our knowledge of the targets for LIF and the consequences of its absence is still …

Cell contacts exhibit a considerable influence on tissue physiology and homeostasis by
controlling paracellular and intercellular transport processes, as well as by affecting …

Successful embryo implantation requires functional luminal epithelia to establish uterine
receptivity and blastocyst-uterine adhesion. During the configuration of uterine receptivity …

Previous studies highlighted chemokines as potential factors regulating changes in the
endometrium during early pregnancy. The current study aimed to screen the effects of a …