As a result of its ability to target certain drugs and/or peptides to the colonic region for the
treatment of several diseases while avoiding systemic absorption and potential side effects …

Delivery of drugs by the oral route remains the most spread route to administer medicines to
patients. The manuscript takes into consideration the most important organs of the digestive …

Poorly soluble drugs are reported to easily degrade in the gastrointestinal tract and
contribute in limiting the effect of drug to its targeted site. Oral administration of drug is one of …

Metronidazole constitutes a mainstay in the antimicrobial therapy of intestinal protozoa, and
is also traditionally considered first-line therapy in cases where there is a requirement to …

This study aimed to advance the development of intestinal colon-coated sustained-release
matrix tablets of metronidazole for diverticulitis treatment, employing the Quality by Design …

The colon provides drug delivery opportunities for colon-specific and systemic delivery of
various therapeutic agents. Different strategies have been utilized in targeting drugs to the …

This review investigates the progression and effectiveness of colon-targeted drug delivery
systems, offering a comprehensive understanding of the colon's anatomy and physiological …

The present work investigates the feasibility of the design of a novel floating elementary
osmotic pump tablet (FEOPT) to prolong the gastric residence of a highly water-soluble drug …

DESIGN AND EVALUATION OF ENTERIC COATED MICROPOROUS OSMOTIC PUMP
TABLET (ECMOPT) OF QUETIAPINE FUMARATE FOR THE TREATMENT OF PSY Page 1 …

Background: Osmotic pump drug delivery systems are one of the most promising and widely
developed systems. They are based on the principle of osmosis and are characterized by a …