Therapeutic potential of hydrogen sulfide in ischemia and reperfusion injury

X Sun, S Wu, C Mao, Y Qu, Z Xu, Y Xie, D Jiang… - Biomolecules, 2024 - mdpi.com
Ischemia–reperfusion (I/R) injury, a prevalent pathological condition in medical practice,
presents significant treatment challenges. Hydrogen sulfide (H2S), acknowledged as the …

Role of hydrogen sulfide in health and disease

YQ Jin, H Yuan, YF Liu, YW Zhu, Y Wang… - MedComm, 2024 - Wiley Online Library
In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent
years, with increased research, we have discovered that H2S can act as an endogenous …

Keap1-Nrf2 pathway up-regulation via hydrogen sulfide mitigates polystyrene microplastics induced-hepatotoxic effects

S Li, M Shi, Y Wang, Y Xiao, D Cai, F Xiao - Journal of Hazardous Materials, 2021 - Elsevier
Microplastics, which are new types of environmental pollutants, are recently receiving
widespread attention worldwide. Hydrogen sulfide (H 2 S) as the third endogenous gaseous …

Testicular torsion in vivo models: Mechanisms and treatments

A Minas, S Mahmoudabadi, NS Gamchi… - …, 2023 - Wiley Online Library
Background Testicular torsion is a condition in which a testis rotates around its longitudinal
axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow …

Pathophysiology and management of testicular ischemia/reperfusion injury: Lessons from animal models

RE Akhigbe, AF Odetayo, TM Akhigbe, MA Hamed… - Heliyon, 2024 - cell.com
Testicular torsion is a urological emergency that involves the twisting of the spermatic cord
along its course. Compelling pieces of evidence have implicated oxidative stress-sensitive …

Salidroside Exerts Beneficial Effect on Testicular Ischemia‐Reperfusion Injury in Rats

SM Wei, YM Huang, ZQ Qin - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Testicular torsion‐detorsion results in testicular ischemia‐reperfusion injury, which is
associated with overgeneration of reactive oxygen species. Salidroside, a major bioactive …

Effects of the apricot diets containing sulfur dioxide at different concentrations on rat testicles

A Yildiz, O Ozhan, A Ulu, T Dogan, B Bakar… - … Science and Pollution …, 2023 - Springer
Due to its antioxidant and antimicrobial properties, sulfur dioxide (SO2) is widely used in
foods and beverages to prevent the growth of microorganisms and to preserve the color and …

Adipose Mesenchymal Stromal Cell‐Derived Exosomes Prevent Testicular Torsion Injury via Activating PI3K/AKT and MAPK/ERK1/2 Pathways

H Liu, M Shi, X Li, W Lu, M Zhang… - Oxidative medicine …, 2022 - Wiley Online Library
Adipose mesenchymal stromal cell‐derived exosomes (ADSC‐Exos) have shown great
potential in the treatment of oxidative stress induced by ischemia‐reperfusion injury …

Remote limb ischemic postconditioning attenuates myocardial dysfunction induced by testicular torsion/detorsion in rats

Q Liu, GW Abbott, J Li, T Liu… - American Journal of …, 2023 - journals.physiology.org
Torsion of the spermatic cord is a urological emergency that must be treated immediately
with surgery, yet detorsion of the testis can cause testicular tissue damage because of …

Hydrogen sulfide and its potential as a possible therapeutic agent in male reproduction

Z Pilsova, A Pilsova, N Zelenkova… - Frontiers in …, 2024 - frontiersin.org
Hydrogen sulfide (H2S) is an endogenously produced signaling molecule that belongs to
the group of gasotransmitters along with nitric oxide (NO) and carbon monoxide (CO). H2S …