The construction of carbon− carbon bonds, along with the creation of stereogenic carbon
centers, continues to be an appealing and demanding area of research, and processes in …

Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

We describe the direct construction of all-carbon quaternary stereocenters via α-
photoalkylation of β-ketocarbonyls with high efficacy and enantioselectivities by merging …

Since the rediscovery of proline in 2000 as catalyst in aldol reaction by List, Barbas and
Lerner and, soon after, the development of iminium catalysis by DWC MacMillan, the …

Domino reactions have received great attention as efficient synthetic methodologies for the
construction of structurally complex molecules from simple materials in a single operation …

Both physical and organic chemists are interested in the cyclopropane ring, the former
owing to the strain inherent to the small ring structure, the latter prompted by the importance …

The interest in cyclopropane derivatives is caused by the facts that, first, the three-carbon
ring is present in quite a few natural and biologically active compounds and, second …

The synthesis of chiral compounds is an important and challenging area of contemporary
synthetic organic chemistry. 1 The broad utility of synthetic chiral molecules has made …

A rapid and efficient organocatalytic cascade sequence for the direct construction of
spirocyclopentane bioxindoles has been carried out by using a chiral squaramide catalyst in …