The field of autoimmune epilepsy has evolved substantially in the last few decades with
discovery of several neural autoantibodies and improved mechanistic understanding of …

Dental caries is a multifactorial chronic disease resulting from the intricate interplay among
acid‐generating bacteria, fermentable carbohydrates, and several host factors such as …

Background Primary amoebic meningoencephalitis (PAM) is a rare, often lethal, cause of
encephalitis, for which early diagnosis and prompt initiation of combination antimicrobials …

Objective Immunodeficient patients are particularly vulnerable to neuroinvasive infections
that can be challenging to diagnose. Metagenomic next generation sequencing can identify …

Metagenomic sequencing is a powerful technique that enables detection of the full spectrum
of pathogens present in any specimen in a single test. Hence, metagenomics is increasingly …

Scleroderma is a chronic autoimmune rheumatic disease associated with widespread tissue
fibrosis and vasculopathy. Approximately two-thirds of all patients with scleroderma present …

Abstract Purpose of Review The goal of this review is to provide an up-to-date approach to
diagnosis and management of patients with central nervous system (CNS) vasculitis. Recent …

Astroviruses are thought to be enteric pathogens. Since 2010, a certain group of
astroviruses has increasingly been recognized, using up-to-date random amplification and …

Background Encephalitis is an inflammatory condition of the brain associated with long-term
neurologic sequelae and even death in children. Although viruses are often implicated, an …

Objectives Central nervous system (CNS) infections account for considerable death and
disability every year. An urgent research priority is scaling up diagnostic capacity, and …