The immune system plays a fundamental role at mucosal barriers in maintaining tissue
homeostasis. This is particularly true for the gut where cells are flooded with microbial …

Killer-cell immunoglobulin-like receptors (KIR) are essential for acquiring natural killer (NK)
cell effector function, which is modulated by a balance between the net input of signals …

Human leukocyte antigen (HLA) class I-specific killer-cell immunoglobulin-like receptors
(KIR) regulate natural killer (NK) cell function in eliminating malignancy. Breast cancer (BC) …

While natural killer (NK) cells are essential players in detection and elimination of malignant
cells, these surveillance properties can be compromised by cancer cells. Since NK cell …

Background Colorectal cancer (CRC) is the most common gastrointestinal malignancy
worldwide, with obesity-induced lipid metabolism disorders playing a crucial role in its …

Killer cell immunoglobulin-like receptors (KIR) consists of activating and inhibitory genes are
essential for natural killer cell education. To determine the association of KIR s with …

Background Variations in the innate and adaptive immune response systems are linked to
variations in the severity of COVID-19. Natural killer cell (NK) function is regulated by …

Acute myeloid leukaemia (AML) is a prevalent haematological malignancy in which various
immune and stromal cells in the bone marrow microenvironment have instrumental roles …

Endometrial cancer (EC) constitutes more than half of all genital cancers in women, with an
increasing incidence in different countries. Natural killer cells (NK cells) are kinds of innate …

Colorectal cancer (CRC) is the most common cause of cancer-related mortality globally. It
ranks as the most common cancer among men and the third most prevalent among women …