Polymer‐based mRNA delivery strategies for advanced therapies

W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …

A review on recent advances in polymer and peptide hydrogels

S Mondal, S Das, AK Nandi - Soft Matter, 2020 - pubs.rsc.org
In this review, we focus on the very recent developments on the use of the stimuli responsive
properties of polymer hydrogels for targeted drug delivery, tissue engineering, and …

[HTML][HTML] Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

Recent advances in the redox-responsive drug delivery nanoplatforms: A chemical structure and physical property perspective

S Mollazadeh, M Mackiewicz… - Materials Science and …, 2021 - Elsevier
Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

Precision cancer nanotherapy: evolving role of multifunctional nanoparticles for cancer active targeting

A Ahmad, F Khan, RK Mishra… - Journal of medicinal …, 2019 - ACS Publications
Nanoparticles with multifunctionality are being designed and formulated to overcome
various limitations of drugs as well as conventional drug delivery systems. Engineered …

Controllable synthesis of calcium carbonate with different geometry: comprehensive analysis of particle formation, cellular uptake, and biocompatibility

H Bahrom, AA Goncharenko… - ACS Sustainable …, 2019 - ACS Publications
Carefully designed micro-and nanocarriers can provide significant advantages over
conventional macroscopic counterparts in drug delivery applications. For the successful …

Advanced bioresponsive multitasking hydrogels in the new era of biomedicine

M Niazi, E Alizadeh, A Zarebkohan… - Advanced Functional …, 2021 - Wiley Online Library
Advanced forms of hydrogels have many inherently desirable properties and can be
designed with different structures and functions. In particular, bioresponsive multifunctional …

Application of bismuth sulfide based nanomaterials in cancer diagnosis and treatment

Z Yang, L Wang, J Zhang, J Liu, X Yu - Nano Today, 2023 - Elsevier
Cancer is still the leading disease threatening human life and health at present. With the
development of nanotechnology, multifunctional nanomaterials integrated with different …

Impact of Macrophages on the Interaction of Cetuximab-Functionalized Polyelectrolyte Capsules with EGFR-Expressing Cancer Cells

G Nifontova, D Kalenichenko, I Kriukova… - … Applied Materials & …, 2023 - ACS Publications
Polyelectrolyte capsules (PCs) are a promising tool for anticancer drug delivery and tumor
targeting. Surface functionalization of PCs with antibodies is widely used for providing their …

Structure–function relationships in polymeric multilayer capsules designed for cancer drug delivery

G Nifontova, T Tsoi, A Karaulov, I Nabiev… - Biomaterials …, 2022 - pubs.rsc.org
The targeted delivery of cancer drugs to tumor-specific molecular targets represents a major
challenge in modern personalized cancer medicine. Engineering of micron and submicron …