The expanded role of chitosan in localized antimicrobial therapy

LM Hemmingsen, N Škalko-Basnet, MW Jøraholmen - Marine Drugs, 2021 - mdpi.com
Chitosan is one of the most studied natural origin polymers for biomedical applications. This
review focuses on the potential of chitosan in localized antimicrobial therapy to address the …

Lipid-based nanocarriers for ocular drug delivery: An updated review

B Das, AK Nayak, S Mallick - Journal of Drug Delivery Science and …, 2022 - Elsevier
Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

Natamycin ocular delivery: challenges and advancements in ocular therapeutics

M Mascarenhas, P Chaudhari, SA Lewis - Advances in Therapy, 2023 - Springer
Fungal keratitis, an ocular fungal infection, is one of the leading causes of monocular
blindness. Natamycin has long been considered the mainstay drug used for treating fungal …

Review of nanoformulations for treating ocular fungal infections

AL Onugwu, SC Emencheta, RN Sabastine… - Journal of Drug Delivery …, 2024 - Elsevier
Ocular fungal infections affect more than one million people globally, of which fungal
keratitis and endophthalmitis are the most common. These infections are the primary cause …

Hyaluronic acid functionalized liposomes embedded in biodegradable beads for duo drugs delivery to oxaliplatin-resistant colon cancer

A Tiwari, V Gajbhiye, A Jain, A Verma, A Shaikh… - Journal of Drug Delivery …, 2022 - Elsevier
Background Oxaliplatin (OHP) resistance is a major hurdle in the chemotherapeutic
treatment of colorectal cancer (CRC). The present study aimed to formulate Eudragit S-100 …

Physiochemical Characterization of Lipidic Nanoformulations Encapsulating the Antifungal Drug Natamycin

L Talarico, I Clemente, A Gennari, G Gabbricci, S Pepi… - Nanomaterials, 2024 - mdpi.com
Natamycin is a tetraene polyene that exploits its antifungal properties by irreversibly binding
components of fungal cell walls, blocking the growth of infections. However, topical ocular …

Bacteriophages as nanocarriers for targeted drug delivery and enhanced therapeutic effects

SC Emencheta, AL Onugwu, CF Kalu, PN Ezinkwo… - Materials …, 2024 - pubs.rsc.org
The effective delivery of therapeutic agents is as important as the active therapeutic agent
because it may make or mar the outcome. Traditional/conventional drug delivery systems …

Thermoresponsive polymers: Phase behavior, drug delivery, and biomedical applications

A Verma, PK Panda, S Mangal, S Bais - Smart Polymeric Nano-Constructs …, 2023 - Elsevier
Thermoresponsive polymers are one of the important tools which can respond to a change
in temperature in a solution. These polymers are categorized based on their responsiveness …

Chitosan-based nanosuspensions for ocular diagnosis and therapy

A Alaimo, OE Pérez - Advanced Nanoformulations, 2023 - Elsevier
Nanotechnology in the biomedical and pharmacology field has awakened a revolution
around its potential application as a diagnostic and therapeutic agent. Nanosuspensions …

Protein and peptide delivery by chitosan systems

A Verma, A Tiwari, S Saraf, PK Panda, A Jain… - Chitosan in Biomedical …, 2022 - Elsevier
Chitin is the most abundant amino-polysaccharide polymer found in nature. Chitosan is the
main derivative of chitin, which is obtained from the alkaline deacetylation of chitin. Because …