Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae
J Rodríguez-Baño, B Gutiérrez-Gutiérrez… - Clinical microbiology …, 2018 - Am Soc Microbiol
Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …
challenging, and some of the few active drugs are not available in many countries. For …
The “old” and the “new” antibiotics for MDR gram-negative pathogens: for whom, when, and how
The recent expansion of multidrug resistant and pan-drug-resistant pathogens poses
significant challenges in the treatment of healthcare associated infections. An important …
significant challenges in the treatment of healthcare associated infections. An important …
[HTML][HTML] Management of KPC-producing Klebsiella pneumoniae infections
M Bassetti, DR Giacobbe, H Giamarellou… - Clinical Microbiology …, 2018 - Elsevier
Background Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-
KP) has become one of the most important contemporary pathogens, especially in endemic …
KP) has become one of the most important contemporary pathogens, especially in endemic …
The management of multidrug-resistant Enterobacteriaceae
M Bassetti, M Peghin, D Pecori - Current Opinion in Infectious …, 2016 - journals.lww.com
Carbapenem-sparing strategies should be used, when feasible, for ESBL infections. The
majority of available nonrandomized studies highlight that combination for CRE seem to …
majority of available nonrandomized studies highlight that combination for CRE seem to …
Fosfomycin as partner drug for systemic infection management. A systematic review of its synergistic properties from in vitro and in vivo studies
RM Antonello, L Principe, AE Maraolo, V Viaggi, R Pol… - Antibiotics, 2020 - mdpi.com
Fosfomycin is being increasingly prescribed for multidrug-resistant bacterial infections. In
patients with systemic involvement, intravenous fosfomycin is usually administered as a …
patients with systemic involvement, intravenous fosfomycin is usually administered as a …
In vitro and in vivo bactericidal activity of ceftazidime-avibactam against Carbapenemase–producing Klebsiella pneumoniae
W Zhang, Y Guo, J Li, Y Zhang, Y Yang, D Dong… - … Resistance & Infection …, 2018 - Springer
Background In recent years, the incidence of carbapenem-resistant Enterobacteriaceae
(CRE) infections has increased rapidly. Since the CRE strain is usually resistant to most of …
(CRE) infections has increased rapidly. Since the CRE strain is usually resistant to most of …
Clinical pharmacokinetics and pharmacodynamics of ceftazidime–avibactam combination: a model-informed strategy for its clinical development
Avibactam is a non-β-lactam, β-lactamase inhibitor of the diazabicyclooctane class that
covalently acylates its β-lactamase targets, encompassing extended spectrum of activities …
covalently acylates its β-lactamase targets, encompassing extended spectrum of activities …
Aztreonam/avibactam effect on pharmacodynamic indices for mutant selection of Escherichia coli and Klebsiella pneumoniae harbouring serine- and New Delhi …
Objectives Ceftazidime/avibactam is not active against MBL-producing bacteria. Combining
ceftazidime/avibactam or avibactam with aztreonam can counter the resistance of MBL …
ceftazidime/avibactam or avibactam with aztreonam can counter the resistance of MBL …
Co-Production of NDM-1 and OXA-232 by ST16 Klebsiella Pneumoniae, Italy, 2016
M Avolio, C Vignaroli, M Crapis… - Future Microbiology, 2017 - Taylor & Francis
Carbapenem-resistant Klebsiella pneumoniae strains, New Delhi metallo-β-lactamase-1
producers, are still rare in Italy, being endemic in Southeast Asiatic region. In October 2016 …
producers, are still rare in Italy, being endemic in Southeast Asiatic region. In October 2016 …
The role of fosfomycin for multidrug-resistant gram-negative infections
The role of fosfomycin for multidrug-resistant gram-negative... : Current Opinion in Infectious
Diseases The role of fosfomycin for multidrug-resistant gram-negative infections : Current …
Diseases The role of fosfomycin for multidrug-resistant gram-negative infections : Current …