Evaluating various algorithms for the inter-subject registration of brain magnetic resonance
images (MRI) is a necessary topic receiving growing attention. Existing studies evaluated …

Motor cortex layer V pyramidal neurons (LVPNs) regulate voluntary control of motor output
and selectively degenerate (along with lower motor neurons) in amyotrophic lateral …

Layer V pyramidal neurons (LVPNs) within the motor cortex integrate sensory cues and co-
ordinate voluntary control of motor output. In amyotrophic lateral sclerosis (ALS) LVPNs and …

Patients with Parkinson's disease (PD) may develop a wide spectrum of non-motor
symptoms during the course of illness. Psychosis is one such commonly observed non …

Amyotrophic lateral sclerosis (ALS) is characterised by the death of upper (corticospinal)
and lower motor neurons (MNs) with progressive muscle weakness. This incurable disease …

The laboratory mouse has been widely used as a model system to investigate the genetic
control mechanisms of mammalian brain development. Magnetic resonance imaging (MRI) …

Dystonias are a group of chronic movement–disabling disorders for which highly effective
oral medications or disease-modifying therapies are lacking. The most effective treatments …

Accumulation of abnormal tau aggregates in the brain is a pathological hallmark of multiple
neurodegenerative disorders including Alzheimer's disease. Increasing evidence suggests …

Social experience is essential for adolescent development and plasticity of social animals.
Deprivation of the experience by social isolation impairs white matter microstructures in the …

Spatial gradients in the initiation and termination of basic processes, such as cytogenesis,
cell-type specification and dendritic maturation, are ubiquitous in developing nervous …