Targeting stress granules in neurodegenerative diseases: A focus on biological function and dynamics disorders

M Fang, Y Liu, C Huang, S Fan - Biofactors, 2024 - Wiley Online Library
Stress granules (SGs) are membraneless organelles formed by eukaryotic cells in response
to stress to promote cell survival through their pleiotropic cytoprotective effects. SGs recruit a …

Insights Into the Links Between Proteostasis and Aging From C. elegans

WH Zhang, S Koyuncu, D Vilchez - Frontiers in Aging, 2022 - frontiersin.org
Protein homeostasis (proteostasis) is maintained by a tightly regulated and interconnected
network of biological pathways, preventing the accumulation and aggregation of damaged …

G3BP1-dependent mechanism suppressing protein aggregation in Huntington's models and its demise upon stress granule assembly

R Gutiérrez-Garcia, S Koyuncu… - Human molecular …, 2023 - academic.oup.com
Stress granules are membrane-less ribonucleoprotein organelles that assemble upon
exposure to stress conditions, but rapidly disassemble upon removal of stress. However …

AMPK‐mediated formation of stress granules is required for dietary restriction‐induced longevity in Caenorhabditis elegans

CT Kuo, GT You, YJ Jian, TS Chen, YC Siao… - Aging …, 2020 - Wiley Online Library
Stress granules (SGs) are nonmembranous organelles that are dynamically assembled and
disassembled in response to various stressors. Under stressed conditions, polyadenylated …

Hybrid Cu2O/TiO2 Nanocomposites with Enhanced Photocatalytic Antibacterial Activity toward Acinetobacter Baumannii

H Li, J Zhong, H Zhu, Y Yang, M Ding… - ACS Applied Bio …, 2019 - ACS Publications
The hybrid Cu2O-TiO2 photocatalytic composite with a pn heterojunction was synthesized
by the supercritical solvothermal route. The uniformly distributed Cu2O was stably combined …

Short-Term Mild Temperature-Stress-Induced Alterations in the C. elegans Phosphoproteome

J Huang, Z Wu, X Zhang - International Journal of Molecular Sciences, 2020 - mdpi.com
Exposure to mild early-life stresses can slow down aging, and protein phosphorylation might
be an essential regulator in this process. However, the mechanisms of phosphorylation …

Tissue-specific effects of temperature on proteasome function

J Pispa, O Matilainen, CI Holmberg - Cell Stress and Chaperones, 2020 - Springer
Variation in ambient growth temperature can cause changes in normal animal physiology
and cellular functions such as control of protein homeostasis. A key mechanism for …

Mulberrin extends lifespan in Caenorhabditis elegans through detoxification function

X Gao, J Yu, L Zhang, H Shi, Y Yan… - Journal of Applied …, 2024 - Wiley Online Library
Mulberrin, a naturally occurring flavone found in mulberry and Romulus Mori, exhibits
diverse biological functions. Here, we showed that mulberrin extended both the lifespan and …

Comparative analysis of quantitative phosphoproteomics between two tilapias (Oreochromis niloticus and Oreochromis aureus) under low-temperature stress

C Yang, H Fan, L Ge, Q Ma, M Jiang, H Wen - PeerJ, 2023 - peerj.com
As an important farmed fish, tilapia has poor tolerance to low-temperatures. At the same
time, different tilapia strains have apparent differences in low-temperature tolerance. In this …

[HTML][HTML] One-day thermal regime extends the lifespan in Caenorhabditis elegans

J Huang, K Wang, M Wang, Z Wu, G Xie, Y Peng… - Computational and …, 2023 - Elsevier
Environmental factors, including temperature, can modulate an animal's lifespan. However,
their underlying mechanisms remain largely undefined. We observed a profound effect of …