FtsZ is the key protein of bacterial cell division and an emergent target for new antibiotics. It
is a filament-forming GTPase and a structural homologue of eukaryotic tubulin. A number of …

Proteins involved in bacterial cell division often do not have a counterpart in eukaryotic cells
and they are essential for the survival of the bacteria. The genetic accessibility of many …

Bacterial cytokinesis is accomplished by the essential 'divisome'machinery. The most widely
conserved divisome component, FtsZ, is a tubulin homolog that polymerizes into the 'FtsZ …

FtsZ is a key molecule in bacterial cell division. In the presence of GTP, it polymerizes into
tubulin-like protofilaments by head-to-tail association. Protofilaments of FtsZ seem to adopt a …

Protein filaments are used in myriads of ways to organize other molecules within cells. Some
filament-forming proteins couple the hydrolysis of nucleotides to their polymerization cycle …

We have investigated the inhibition by SulA of the assembly of Escherichia coli FtsZ. Using
quantitative GTPase and fluorescence assays, we found that SulA inhibition resulted in an …

The spatiotemporal regulation of cell division is a fundamental issue in cell biology. Bacteria
have evolved a variety of different systems to achieve proper division site placement. In …

The spatial and temporal control of Filamenting temperature sensitive mutant Z (FtsZ) Z-ring
formation is crucial for proper cell division in bacteria. In Escherichia coli, the synthetic lethal …

Protein halogenation is a common non-enzymatic post-translational modification
contributing to aging, oxidative stress-related diseases and cancer. Here, we report a …

Cytoskeletal structures are dynamically remodeled with the aid of regulatory proteins. FtsZ
(filamentation temperature-sensitive Z) is the bacterial homolog of tubulin that polymerizes …