Low-dose non-targeted effects and mitochondrial control
D Averbeck - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …
[HTML][HTML] Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response
E McCann, J O'Sullivan, S Marcone - Translational oncology, 2021 - Elsevier
Radiotherapy is a regimen that uses ionising radiation (IR) to treat cancer. Despite the
availability of several therapeutic options, cancer remains difficult to treat and only a minor …
availability of several therapeutic options, cancer remains difficult to treat and only a minor …
Mitochondrial control of genomic instability in cancer
Simple Summary Cancer cells display among its hallmark genomic instability. This is a
progressive tendency in accumulate genome alteration which contributes to the damage of …
progressive tendency in accumulate genome alteration which contributes to the damage of …
Energy metabolism is altered in radioresistant rectal cancer
CE Buckley, X Yin, S Meltzer, AH Ree… - International Journal of …, 2023 - mdpi.com
Resistance to neoadjuvant chemoradiation therapy is a significant clinical challenge in the
management of rectal cancer. There is an unmet need to identify the underlying …
management of rectal cancer. There is an unmet need to identify the underlying …
MicroRNA profiling in oesophageal adenocarcinoma cell lines and patient serum samples reveals a role for miR-451a in radiation resistance
F Butz, AK Eichelmann, GC Mayne, T Wang… - International journal of …, 2020 - mdpi.com
Many patients with Oesophageal Adenocarcinoma (OAC) do not benefit from
chemoradiotherapy treatment due to therapy resistance. To better understand the …
chemoradiotherapy treatment due to therapy resistance. To better understand the …
Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the …
AB Heeran, J McCready, MR Dunne, NE Donlon… - Metabolites, 2021 - mdpi.com
Oesophageal adenocarcinoma (OAC) is an exemplar model of obesity-associated cancer.
Previous work in our group has demonstrated that overweight/obese OAC patients have …
Previous work in our group has demonstrated that overweight/obese OAC patients have …
30th Annual GP2A Medicinal Chemistry Conference
The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held their
30th annual conference in August 2022 in Trinity College Dublin, Ireland. There were 9 …
30th annual conference in August 2022 in Trinity College Dublin, Ireland. There were 9 …