Biphenyl derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity

M Mammen, S Dunham, A Hughes - US Patent App. 10/778,649, 2004 - Google Patents
This invention provides biphenyl derivatives containing (i) a (biphenyl-2-yl)
oxycarbonylamino-or (biphenyl-2-yl) ami nocarbonylamino-Substituted (2-7C) azacycloalkyl …

Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity

M Mammen, S Dunham - US Patent 7,345,060, 2008 - Google Patents
5,846,989 A 12/1998 Bonnert et al. 5,929, 100 A 7, 1999 Bonnert et al. I 5,973,167 A 10,
1999 Bonnert et al. 5,977,384 A 11/1999 Bonnert et al. R!).--n 6,008,365. A 12/1999 Bonnert …

Biphenyl compounds useful as muscarinic receptor antagonists

M Mammen, YH Ji, YQ Mu, C Husfeld, L Li - US Patent 7,288,657, 2007 - Google Patents
The present invention provides novel biphenyl com pounds having muscarinic receptor
antagonist or anticho linergic activity. Among other properties, compounds of this invention …

Biphenyl compounds useful as muscarinic receptor antagonists

M Mammen, YH Ji, YQ Mu, C Husfeld, L Li - US Patent 7,265,133, 2007 - Google Patents
R4 whereina, b, c, m, p, s, t, W. Ar", X', RRRRR and R7 are as defined specification. The
compounds of formula I are muscarinic receptor antagonists. The invention also provides …

Biphenyl compounds useful as muscarinic receptor antagonists

M Mammen, YH Ji, YQ Mu, T Mischki… - US Patent …, 2008 - Google Patents
The present invention provides novel biphenyl compounds having muscarinic receptor
antagonist or anticholinergic activity. Among other properties, compounds of this inven tion …

Biphenyl compounds useful as muscarinic receptor antagonists

YQ Mu, YH Ji, M Mammen, EL Stangeland - US Patent 7,642,355, 2010 - Google Patents
The present invention provides novel biphenyl compounds having muscarinic receptor
antagonist or anticholinergic activity. Among other properties, compounds of the invention …

Method and system for providing employer-sponsored retirement plan

DP Herr, RJ Toth - US Patent 8,429,052, 2013 - Google Patents
A computer-implemented method of administering income distributions from an employer-
sponsored retirement plan having a participant account value provides an option to a plan …

Dialkylphenyl compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity

PJ Colson, AD Hughes, C Husfeld, M Mammen… - US Patent …, 2009 - Google Patents
2003, OO18019 A1 1/2003 Meade et al. 2004O167167 A1 8/2004 Mammen et al.
2004/0209860 A1 10, 2004 Mammen et al. 2004/0209915 A1 10, 2004 Mammen et al …

Crystalline form of a biphenyl compound

RS Chao, M Rapta, PJ Colson - US Patent 7,521,558, 2009 - Google Patents
The present invention provides crystalline 1, 2-ethanedis ulfonic acid salts of biphenyl-2-
ylcarbamic acid 1-2-(2-chloro-4-((R)-2-hydroxy-2-(8-hydroxy-2-oxo-1, 2-dihyd roquinolin-5 …

Biphenyl compounds useful as muscarinic receptor antagonists

YH Ji, C Husfeld, M Mammen, YQ Mu… - US Patent …, 2009 - Google Patents
The present invention provides novel biphenyl compounds having muscarinic receptor
antagonist or anticholinergic activity. Among other properties, compounds of the invention …