Cartilage injuries are typically caused by trauma, chronic overload, and autoimmune
diseases. Owing to the avascular structure and low metabolic activities of chondrocytes …

Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …

Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Articular cartilage is a load‐bearing tissue playing a crucial mechanical role in diarthrodial
joints, facilitating joint articulation, and minimizing wear. The significance of biomechanical …

Adult articular cartilage exhibits little capacity for intrinsic repair, and thus even minor injuries
or lesions may lead to progressive damage and osteoarthritic joint degeneration, resulting in …

The intervertebral disc (IVD) is a moderately moving joint that is located between the bony
vertebrae and provides flexibility and load transmission throughout the spinal column. The …

Background Worldwide, many people suffer from knee injuries and articular cartilage
damage every year, which causes pain and reduces productivity, life quality, and daily …

Cartilage defects in the knee are being diagnosed with increased frequency and are treated
with a variety of techniques. The aim of any cartilage repair procedure is to generate the …

The use of tissue-engineered articular cartilage (TEAC) constructs has the potential to
become a powerful treatment option for cartilage lesions resulting from trauma or early …

There is no long-term treatment strategy for young and active patients with cartilage defects.
Early and effective joint preserving treatments in these patients are crucial in preventing the …