Objective. Corneal neovascularization is a sight-threatening condition affecting more than
1.4 million people per year. Left untreated, it can lead to tissue scarring, oedema, lipid …

The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …

The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

Contact lens-related problems are common and can result in severe sight-threatening
complications or contact lens drop out if not addressed properly. We systematically reviewed …

In contrast to the conventional ocular formulations, contact lenses are well known for their
diverse applications ranging from bio-sensing, prevention of myopia, cosmetics, and drug …

The cornea actively maintains its own avascular status to preserve its ultimate optical
function. This corneal avascular state is also defined as “corneal angiogenic privilege” …

Corneal neovascularization is a sight-threatening condition caused by angiogenesis in the
normally avascular cornea. Neovascularization of the cornea is often associated with an …

Corneal neovascularization (CNV) is a common clinical finding seen in a range of eye
diseases. Current therapeutic approaches to treat corneal angiogenesis, in which vascular …

Corneal transplantation has been proven effective for returning the gift of sight to those
affected by corneal disorders such as opacity, injury, and infections that are a leading cause …

Biologics, like peptides, proteins and nucleic acids, have proven to be promising drugs for
the treatment of numerous diseases. However, besides the off label use of the monoclonal …