Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …

Background Malaria and neglected communicable protozoa parasitic diseases, such as
leishmaniasis, and trypanosomiasis, are among the otherwise called diseases for neglected …

Heterocycles are particularly common moieties within marine natural products. Specifically,
tetrahydrofuranyl rings are present in a variety of compounds which present complex …

Neglected Tropical Diseases (NTD) represent a serious threat to humans, especially for
those living in poor or developing countries. Almost one-sixth of the world population is at …

Revived analysis interests in natural products in the hope of discovering new and novel
antileishmanial drug leads have been driven partially by the increasing incidence of drug …

Despite advancements in the areas of omics and chemoinformatics, potent novel
biotherapeutic molecules with new modes of actions are needed for leishmaniasis. The …

Leishmaniasis and Chagas disease, two of the most prevalent neglected tropical diseases,
are a world health problem. The harsh reality of these infective diseases is the absence of …

Among neglected tropical diseases, leishmaniasis is one of the leading causes, not only of
deaths but also of disability-adjusted life years. This disease, caused by protozoan parasites …

Leishmaniasis produces approximately-one million of new cases annually, making it one of
the most important tropical diseases. As current treatments are not fully effective and are …

Current therapies of leishmaniasis and Chagas disease, two of the most widespread
neglected tropical diseases, have limited efficacy and toxic side effects. In this regard …