Integrated analysis of transcriptomic and proteomic data
Until recently, understanding the regulatory behavior of cells has been pursued through
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
Proteomics in evolutionary ecology: linking the genotype with the phenotype
AP Diz, M MARTÍNEZ‐FERNÁNDEZ… - Molecular …, 2012 - Wiley Online Library
The study of the proteome (proteomics), which includes the dynamics of protein expression,
regulation, interactions and its function, has played a less prominent role in evolutionary and …
regulation, interactions and its function, has played a less prominent role in evolutionary and …
AON-mediated exon skipping restores ciliation in fibroblasts harboring the common Leber congenital amaurosis CEP290 mutation
X Gerard, I Perrault, S Hanein, E Silva, K Bigot… - … Therapy-Nucleic Acids, 2012 - cell.com
Leber congenital amaurosis (LCA) is a severe hereditary retinal dystrophy responsible for
congenital or early-onset blindness. The most common disease-causing mutation (> 10%) is …
congenital or early-onset blindness. The most common disease-causing mutation (> 10%) is …
Multi-pathway protective effects of microRNAs on human chondrocytes in an in vitro model of osteoarthritis
RN Al-Modawi, JE Brinchmann, TA Karlsen - Molecular Therapy-Nucleic …, 2019 - cell.com
Osteoarthritis (OA) is the most common degenerative joint disease. One of the main
pathogenic factors of OA is thought to be inflammation. Other factors associated with OA are …
pathogenic factors of OA is thought to be inflammation. Other factors associated with OA are …
[HTML][HTML] The effect of exposure time and concentration of airborne PM2. 5 on lung injury in mice: A transcriptome analysis
H Wang, X Shen, J Liu, C Wu, J Gao, Z Zhang, F Zhang… - Redox biology, 2019 - Elsevier
The association between airborne fine particulate matter (PM 2.5) concentration and the risk
of respiratory diseases has been well documented by epidemiological studies. However, the …
of respiratory diseases has been well documented by epidemiological studies. However, the …
β-Arrestin/Ral signaling regulates lysophosphatidic acid–mediated migration and invasion of human breast tumor cells
TT Li, M Alemayehu, AI Aziziyeh, C Pape… - Molecular Cancer …, 2009 - AACR
The lipid mediator lysophosphatidic acid (LPA) plays a role in cancer progression and
signals via specific G protein–coupled receptors, LPA1-3. LPA has been shown to enhance …
signals via specific G protein–coupled receptors, LPA1-3. LPA has been shown to enhance …
Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid …
HJ Speirs, RW Brown - Journal of Endocrinology, 2004 - joe.bioscientifica.com
The cDNA sequences encoding three GnRH forms, sea bream GnRH (sbGnRH), salmon
GnRH (sGnRH) and chicken GnRH II (cGnRH II), were cloned from the brain of European …
GnRH (sGnRH) and chicken GnRH II (cGnRH II), were cloned from the brain of European …
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
Background Ovarian cancer is the main cause of gynecological cancer-associated death.
However, 5-year survival rates differ dramatically between the five main ovarian carcinoma …
However, 5-year survival rates differ dramatically between the five main ovarian carcinoma …
Differentiating infection, colonisation, and sterile inflammation in critical illness: the emerging role of host-response profiling
M Jeffrey, KJ Denny, J Lipman… - Intensive Care Medicine, 2023 - Springer
Infection results when a pathogen produces host tissue damage and elicits an immune
response. Critically ill patients experience immune activation secondary to both sterile and …
response. Critically ill patients experience immune activation secondary to both sterile and …