Parvoviruses, infecting vertebrates and invertebrates, are a family of single-stranded DNA
viruses with small, non-enveloped capsids with T= 1 icosahedral symmetry. A quarter of a …

Adeno-associated viral vectors (AAVs) are increasingly useful preclinical tools in
neuroscience research studies for interrogating cellular and neurocircuit functions and …

Over the last two decades, gene therapy vectors based on wild‐type Adeno‐associated
viruses (AAV) are safe and efficacious in numerous clinical trials and are translated into …

Adeno-associated virus (AAV) has a single-stranded DNA genome encapsidated in a small
icosahedrally symmetric protein shell with 60 subunits. AAV is the leading delivery vector in …

Human gene therapy has advanced from twentieth-century conception to twenty-first-century
reality. The recombinant Adeno-Associated Virus (rAAV) is a major gene therapy vector …

The capsid structures of most Adeno-associated virus (AAV) serotypes, already assigned to
an antigenic clade, have been previously determined. This study reports the remaining …

Adeno-associated viruses (AAVs) are small nonenveloped single-stranded DNA (ssDNA)
viruses that are currently being developed as gene therapy biologics. After cell entry, AAVs …

This review is a partially personal account of the discovery of virus structure and its
implication for virus function. Although I have endeavored to cover all aspects of structural …

Communicable respiratory viral infections pose both epidemic and pandemic threats and
broad-spectrum antiviral strategies could improve preparedness for these events. To …

Adeno-associated viruses (AAVs) have become important therapeutic gene delivery vectors
in recent years. However, there are challenges, including intractable tissues/cell types and …