The study of plant mitochondria started in earnest around 1950 with the first isolations of
mitochondria from animal and plant tissues. The first 35 years were spent establishing the …

To understand complex biological systems requires the integration of experimental and
computational research—in other words a systems biology approach. Computational …

Mitochondria play a pivotal role in energy metabolism, programmed cell death and oxidative
stress. Mutated mitochondrial DNA in diseased cells compromises the structure of key …

Oxidative stress resulting from increased availability of reactive oxygen species (ROS) is a
key component of many responses of plants to challenging environmental conditions. The …

It has been 75 yr since leaf respiratory metabolism in the light (day respiration) was
identified as a low‐flux metabolic pathway that accompanies photosynthesis. In principle, it …

The tricarboxylic acid (TCA) cycle is a crucial component of respiratory metabolism in both
photosynthetic and heterotrophic plant organs. All of the major genes of the tomato TCA …

Mitochondria are key players in plant cell redox homeostasis and signalling. Earlier
concepts that regarded mitochondria as secondary to chloroplasts as the powerhouses of …

We have developed genetically encoded fluorescent sensors for reduced nicotinamide
adenine dinucleotide (NADH), which manifest a large change in fluorescence upon NADH …

The electron transport chain in mitochondria of different organisms contains a mixture of
common and specialised components. The specialised enzymes form branches to the …

Recent years have seen considerable advances in our understanding of the particular
physiological roles of the constituent enzymes of the tricarboxylic acid (TCA) cycle. Despite …