Antihypertensive activity of a quinoline appended chalcone derivative and its site specific binding interaction with a relevant target carrier protein

H Kumar, V Devaraji, R Joshi, M Jadhao, P Ahirkar… - RSC …, 2015 - pubs.rsc.org
Inhibition of Angiotensin Converting Enzyme (ACE) is identified as a main therapeutic target
in controlling hypertension. The principal intent of this work is to investigate the ACE …

Interaction of tetradecyltrimethylammonium bromide with bovine serum albumin in different compositions: Effect of temperatures and electrolytes/urea

J Abedin, S Mahbub, MM Rahman, A Hoque… - Chinese Journal of …, 2021 - Elsevier
Herein, the interaction of a protein, bovine serum albumin (BSA), with
tetradecyltrimethylammonium bromide (TTAB, a cationic surfactant), has been investigated …

The thiol of human serum albumin: Acidity, microenvironment and mechanistic insights on its oxidation to sulfenic acid

J Bonanata, L Turell, L Antmann, G Ferrer-Sueta… - Free Radical Biology …, 2017 - Elsevier
Human serum albumin (HSA) has a single reduced cysteine residue, Cys34, whose acidity
has been controversial. Three experimental approaches (pH-dependence of reactivity …

Modulation of the protein–ligand interaction in the presence of graphene oxide: A detailed spectroscopic study

A Bapli, A Chatterjee, RK Gautam, R Jana, D Seth - Langmuir, 2021 - ACS Publications
Several applications of graphene oxide (GO) have been established over the years, and it
has the potential to be used as a biomedical material. Studying the effect of GO on protein …

Stabilization of Human Serum Albumin by the Binding of Phycocyanobilin, a Bioactive Chromophore of Blue-Green Alga Spirulina: Molecular Dynamics and …

M Radibratovic, S Minic, D Stanic-Vucinic, M Nikolic… - PLoS …, 2016 - journals.plos.org
Phycocyanobilin (PCB) binds with high affinity (2.2 x 106 M-1 at 25° C) to human serum
albumin (HSA) at sites located in IB and IIA subdomains. The aim of this study was to …

A specific and biocompatible fluorescent sensor based on the hybrid of GFP chromophore and peptide for HSA detection

C Liao, F Li, S Huang, B Zheng, J Du, D Xiao - Biosensors and …, 2016 - Elsevier
It is still a challenge for clinical diagnostics to design non-toxic and selective sensors for a
specific analyte in blood serum, which contains a large number of proteins, small molecules …

Selectively switching on europium emission in drug site one of human serum albumin

S Shuvaev, R Pal, D Parker - Chemical Communications, 2017 - pubs.rsc.org
Selectively switching on europium emission in drug site one of human serum albumin -
Chemical Communications (RSC Publishing) DOI:10.1039/C7CC03071A Royal Society of …

Is the Sudlow site I of human serum albumin more generous to adopt prospective anti-cancer bioorganic compound than that of bovine: A combined spectroscopic and …

R Joshi, M Jadhao, H Kumar, SK Ghosh - Bioorganic Chemistry, 2017 - Elsevier
A comparative biophysical study on the individual conformational adaptation embraced by
two homologous serum albumins (SA)(bovine and human) towards a potential anticancer …

Diketo modification of curcumin affects its interaction with human serum albumin

SAM Shaikh, BG Singh, A Barik, MV Ramani… - … Acta Part A: Molecular …, 2018 - Elsevier
Curcumin isoxazole (CI) and Curcumin pyrazole (CP), the diketo modified derivatives of
Curcumin (CU) are metabolically more stable and are being explored for pharmacological …

Molecular recognition based rapid diagnosis of immunoglobulins via proteomic profiling of protein-nanoparticle complexes

AI Dar, S Walia, A Acharya - International journal of biological …, 2019 - Elsevier
Abstract Protein-nanoparticle (NP) interaction, which inevitably form protein corona (PC),
has been the subject of much debate about its role in modern biomedical research. In this …