The chemical constituents of the Cannabis plant known as cannabinoids have been
extensively researched for their potential therapeutic benefits. The use of cannabinoids …

Oxidative stress is among the major triggers for many important human functional disorders,
which often lead to various metabolic or tissue diseases. The aim of the study is to obtain …

Introduction Montelukast is a leukotriene inhibitor that is widely used to treat chronic asthma
and allergic rhinitis. The drug interferes with molecular signaling pathways produced by …

Since medicinal plants are widely used in treating various diseases, phytoconstituents
enrichment strategies are of high interest for plant growers. First of all, we investigated the …

Lipid metabolism dysregulation can lead to dyslipidemia and obesity, which are major
causes of cardiovascular disease and associated mortality worldwide. The purpose of the …

Endothelial dysfunction is the basis of the physiopathological mechanisms of vascular
diseases. In addition to the therapeutic activity of plant extracts, cytotoxicity is significant …

Background and purpose Tubocurarine (d-TC), a non-depolarizing competitive blocker of
nicotinic acetylcholine receptors is extensively utilized for the relaxation of skeletal muscles …

Chemotherapy-induced peripheral neuropathy is one of the most common side effects of
anticancer therapy. It is anticipated that chemotherapies with different mechanisms of action …

Pain is one of the most common symptoms experienced by patients. The use of current
analgesics is limited by low efficacy and important side effects. Transient receptor potential …

Osteoarthritis is characterized by progressive articular cartilage degradation, subchondral
bone changes, and synovial inflammation, and affects various joints, causing pain and …