[HTML][HTML] Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research

EK Elmahallawy, AAM Alkhaldi, AA Saleh - Biomedicine & …, 2021 - Elsevier
Leishmaniasis, a neglected parasitic disease caused by a unicellular protozoan of the
genus Leishmania, is transmitted through the bite of a female sandfly. The disease remains …

What makes mucosal and anergic diffuse cutaneous leishmaniases so clinically and immunopathogically different? A review in Brazil

FT Silveira - Transactions of the Royal Society of Tropical …, 2019 - academic.oup.com
American cutaneous leishmaniasis (ACL) is a parasitic protozoan disease caused by
different Leishmania species widely distributed throughout Latin America. Fifteen …

Macrophage Polarization in the Skin Lesion Caused by Neotropical Species of Leishmania sp

CM Sandoval Pacheco… - Journal of …, 2021 - Wiley Online Library
Macrophages play important roles in the innate and acquired immune responses against
Leishmania parasites. Depending on the subset and activation status, macrophages may …

Leishmania braziliensis Infection Enhances Toll-Like Receptors 2 and 4 Expression and Triggers TNF-α and IL-10 Production in Human Cutaneous Leishmaniasis

LP Polari, PP Carneiro, M Macedo… - Frontiers in cellular …, 2019 - frontiersin.org
Cutaneous leishmaniasis (CL) caused by infection with Leishmania braziliensis is
characterized by an exaggerated inflammatory response that controls the parasite burden …

Blockade of TLR2 and TLR4 attenuates inflammatory response and parasite load in cutaneous leishmaniasis

PP Carneiro, AS Dórea, WN Oliveira… - Frontiers in …, 2021 - frontiersin.org
Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized
by a pronounced inflammatory response associated with ulcer development. Monocytes …

The Paradox of a Phagosomal Lifestyle: How Innate Host Cell-Leishmania amazonensis Interactions Lead to a Progressive Chronic Disease

MB Carneiro, NC Peters - Frontiers in Immunology, 2021 - frontiersin.org
Intracellular phagosomal pathogens represent a formidable challenge for innate immune
cells, as, paradoxically, these phagocytic cells can act as both host cells that support …

The extraordinary case of a woman with a 30-year-long diffuse leishmaniasis cured with one single ampoule of intranasal pentavalent antimoniate

SVCB Gonçalves, DL Costa, JJ Cantinho-Junior… - Pathogens, 2023 - mdpi.com
Infection with Leishmania amazonensis and L. mexicana may lead to diffuse cutaneous
leishmaniasis. The cure is exceptional, especially for the strange case of this lady. Case …

In silico designing of a novel polyvalent multi-subunit peptide vaccine leveraging cross-immunity against human visceral and cutaneous leishmaniasis: an …

M Bhattacharjee, M Banerjee, A Mukherjee - Journal of Molecular …, 2023 - Springer
Context Leishmaniasis is a group of vector-borne infectious diseases caused by over 20
pathogenic Leishmania species that are endemic in many tropical and subtropical countries …

Multiparametric analysis of host and parasite elements in new world tegumentary leishmaniasis

BC de Carvalho, T Vital, J Osiro, CM Gomes… - Frontiers in Cellular …, 2022 - frontiersin.org
Tegumentary leishmaniasis is a tropical disease caused by protozoa of the genus
Leishmania. Clinically, the disease presents a broad spectrum of symptoms, the …

Toll-like receptors 2, 4 and 7, interferon-gamma and interleukin 10, and programmed death ligand 1 transcripts in skin from dogs of different clinical stages of …

L Ordeix, S Montserrat-Sangrà, P Martínez-Orellana… - Parasites & vectors, 2019 - Springer
Abstract Background Canine leishmaniosis (CanL) caused by Leishmania infantum can
have several dermatological manifestations. The type of immune response elicited against …