Applications of clustering algorithms in biomedical research are ubiquitous, with typical
examples including gene expression data analysis, genomic sequence analysis, biomedical …

Background We present the results of EGASP, a community experiment to assess the state-
of-the-art in genome annotation within the ENCODE regions, which span 1% of the human …

This is the first book to take a truly comprehensive look at clustering. It begins with an
introduction to cluster analysis and goes on to explore: proximity measures; hierarchical …

Abstract The University of California Santa Cruz Genome Browser Database (GBD) contains
sequence and annotation data for the genomes of about a dozen vertebrate species and …

Today, scientists and engineers are exploring advanced applications and uses of immersive
systems that can be cost-effectively applied in their fields. However, one of the impediments …

Understanding the molecular mechanisms responsible for the regulation of the
transcriptome present in eukaryotic cells is one of the most challenging tasks in the …

Background Hsp70 chaperones are required for key cellular processes and response to
environmental changes and survival but they have not been fully characterized yet. The …

Short proteins play key roles in cell signalling and other processes, but their abundance in
the mammalian proteome is unknown. Current catalogues of mammalian proteins exhibit an …

The complexities of tumor genomes are rapidly being uncovered, but how they are regulated
into functional proteomes remains poorly understood. Standard proteomics workflows use …

Alternative splicing and gene duplication are two major sources of proteomic function
diversity. Here, we study the evolutionary trend of alternative splicing after gene duplication …