Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …

Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …

Background CV9103 is a prostate-cancer vaccine containing self-adjuvanted mRNA
(RNActive®) encoding the antigens PSA, PSCA, PSMA, and STEAP1. This phase I/IIa study …

In addition to sperm cells, seminal fluid contains various small membranous vesicles. These
include prostasomes, membrane vesicles secreted by prostate epithelial cells. Prostasomes …

New treatment options especially of solid tumors including for metastasized prostate cancer
(PCa) are urgently needed. Recent treatments of leukemias with chimeric antigen receptors …

The human bronchial epithelium is composed of multiple distinct cell types that cooperate to
defend against environmental insults. While studies have shown that smoking alters …

Background: Prostate cancer is one of the most widespread cancers in the world. Early
diagnosis is the most important factor in treatment efficiency. Furthermore, new methods for …

Through a genome-wide association analysis with a total of 7,035 individuals with duodenal
ulcer and 25,323 controls from Japan, we identified two susceptibility loci at the PSCA gene …

Simple Summary Cancer treatments have significantly changed with the introduction of
immunotherapy. Recently, the development of new agents that harness the redirection of T …

Chemotherapy is one of the most widely used approaches in combating advanced prostate
cancer, but its therapeutic efficacy is usually insufficient due to poor specificity and …