Optimal perioperative management of arterial blood pressure

L Lonjaret, O Lairez, V Minville… - Integrated blood pressure …, 2014 - Taylor & Francis
Perioperative blood pressure management is a key factor of patient care for anesthetists, as
perioperative hemodynamic instability is associated with cardiovascular complications …

Unraveling interactions between anesthetics and the endothelium: update and novel insights

JA Aguirre, E Lucchinetti, AS Clanachan… - Anesthesia & …, 2016 - journals.lww.com
The vascular endothelium is one of the largest organs in the body and consists of a single
layer of highly specialized cells with site-specific morphology and functions. Endothelial …

[PDF][PDF] Effects of ketamine, propofol, and ketofol on proinflammatory cytokines and markers of oxidative stress in a rat model of endotoxemia-induced acute lung injury.

D Gokcinar, V Ergin, A Cumaoglu… - Acta Biochimica …, 2013 - frontierspartnerships.org
Intravenous lipopolysaccharide (LPS) leads to acute lung injury (ALI) in rats. The purpose of
this study was to examine the anti-inflammatory and antioxidant efficacy of ketamine …

Protein kinase C isoforms distinctly regulate propofol-induced endothelium-dependent and endothelium-independent vasodilation

Y Wang, H Zhou, B Wu, Q Zhou, D Cui… - Journal of …, 2015 - journals.lww.com
Protein kinase C (PKC) isoforms improve endothelial nitric oxide synthase activity and
contractile Ca 2+ sensitivity in blood vessels. These actions may have opposite effects on …

The effect of intravenous dexamethasone and lidocaine on propofol‐induced vascular pain: a randomized double‐blinded placebo‐controlled trial

S Ahmad, GS De Oliveira Jr… - Pain research and …, 2013 - Wiley Online Library
Background. The mechanism for pain associated with intravenous administration of propofol
is believed to be related to the release of nitric oxide. We hypothesized that pain following …

Regulatory effects of anesthetics on nitric oxide

W Fan, Q Liu, X Zhu, Z Wu, D Li, F Huang, H He - Life sciences, 2016 - Elsevier
Nitric oxide (NO) is a free radical gas in the biological system, which is produced by nitric
oxide synthase (NOS) family. NO acts as a biological mediator and plays important roles in …

Angiotensin converting enzyme inhibitors enhance the hypotensive effects of propofol by increasing nitric oxide production

GH Oliveira-Paula, LC Pinheiro, GC Ferreira… - Free Radical Biology …, 2018 - Elsevier
Propofol anesthesia is usually accompanied by hypotension. Studies have shown that the
hypotensive effects of propofol increase in patients treated with angiotensin-converting …

Quinapril decreases antifibrinolytic and prooxidative potential of propofol in arterial thrombosis in hypertensive rats

M Wojewodzka-Zelezniakowicz… - Journal of the Renin …, 2016 - journals.sagepub.com
Angiotensin converting enzyme inhibitors and propofol both exert hypotensive action and
may affect hemostasis. We investigated the influence of quinapril and propofol on …

Magnesium sulfate plus lidocaine reduces propofol injection pain: a double-blind, randomized study

J Sun, R Zhou, W Lin, J Zhou, W Wang - Clinical Therapeutics, 2016 - Elsevier
Purpose Propofol injection can cause distressing pain, and no method can inhibit it
completely. Neither lidocaine nor magnesium sulfate (MgSO 4) was sufficient to prevent pain …

The impact of advancing age on postoperative outcomes in plastic surgery

K Shih, GS De Oliveira Jr, C Qin, JY Kim - Journal of Plastic, Reconstructive …, 2015 - Elsevier
Age has been shown to be an independent predictor of complications in general surgery
patients. In contrast, the effect of age on outcomes after plastic surgery has yet to be …