Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Nano-drug delivery systems for T cell-based immunotherapy

R Li, Z Chen, J Li, Z Dai, Y Yu - Nano Today, 2022 - Elsevier
T cell-based immunotherapy, which tackles T cell dysfunction and exhaustion, offers broad
promising for treating cancer. Various T cell-based immunotherapies, such as immune …

[HTML][HTML] Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance …

C Ji, J Si, Y Xu, W Zhang, Y Yang, X He, H Xu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Sonodynamic therapy (SDT) is a promising strategy to inhibit tumor growth and
activate antitumor immune responses for immunotherapy. However, the hypoxic and …

Oxygen‐enriched metal‐phenolic X‐ray nanoprocessor for cancer radio‐radiodynamic therapy in combination with checkpoint blockade immunotherapy

W Sang, L Xie, G Wang, J Li, Z Zhang, B Li… - Advanced …, 2021 - Wiley Online Library
Radiotherapy (RT) based on DNA damage and reactive oxygen species (ROS) generation
has been clinically validated in various types of cancer. However, high dose‐dependent …

Plasmonic-Fluorescent Janus Ag/Ag2S Nanoparticles for In Situ H2O2-Activated NIR-II Fluorescence Imaging

X Zhang, W Wang, L Su, X Ge, J Ye, C Zhao, Y He… - Nano Letters, 2021 - ACS Publications
Silver sulfide (Ag2S) has gained widespread attention in second near-infrared (950–1700
nm, NIR-II) window imaging because of its high fluorescence quantum yield and low toxicity …

Programmed nanoreactors Boost Immune Response through ROS Cascade amplification along with RNS storm

H Tian, Y Li, J Lin, F Zhu, Z Hou, P Wang… - ACS Materials …, 2023 - ACS Publications
High oxidative stress plays a significant role in activating intracellular signaling pathways
that govern immunogenic cell death (ICD). Nevertheless, immune response is often confined …

Tumor microenvironment-responsive Ag2S-PAsp (DOX)-cRGD nanoparticles-mediated photochemotherapy enhances the immune response to tumor therapy

R Han, Q Liu, Y Lu, J Peng, M Pan, GH Wang, W Chen… - Biomaterials, 2022 - Elsevier
Chemotherapy drugs play important roles in clinical treatment, and most first-line regimens
of cancer therapy contain chemotherapy drugs. In particular, some chemotherapeutic drugs …

Ag2S nanoparticle-mediated multiple ablations reinvigorates the immune response for enhanced cancer photo-immunotherapy

R Han, Y Xiao, Q Yang, M Pan, Y Hao, X He, J Peng… - Biomaterials, 2021 - Elsevier
Photothermal therapy (PTT) has been widely used in cancer treatment in recent years.
However, it is difficult to completely eliminate tumors by single PTT, and the effects of single …

Radiotherapy combined with nano-biomaterials for cancer radio-immunotherapy

Q Dong, T Xue, H Yan, F Liu, R Liu, K Zhang… - Journal of …, 2023 - Springer
Radiotherapy (RT) plays an important role in tumor therapy due to its noninvasiveness and
wide adaptation. In recent years, radiation therapy has been discovered to induce an anti …

State-of-the-Art and Perspectives for Nanomaterials Combined with Nitric Oxide Donors: From Biomedical to Agricultural Applications

JC Pieretti, MT Pelegrino, NM Silveira… - ACS Applied Nano …, 2023 - ACS Publications
The free radical nitric oxide (NO) is a signaling molecule that controls several important
physiological and pathophysiological processes in mammals and in plants. In humans, the …