A double‐edged sword with therapeutic potential: an updated role of autophagy in ischemic cerebral injury

K Wei, P Wang, CY Miao - CNS neuroscience & therapeutics, 2012 - Wiley Online Library
Cerebral ischemia is a severe outcome that could cause cognitive and motor dysfunction,
neurodegenerative diseases and even acute death. Although the existence of autophagy in …

Vitamin-D deficiency as a potential environmental risk factor in multiple sclerosis, schizophrenia, and autism

E Kočovská, F Gaughran, A Krivoy, UC Meier - Frontiers in psychiatry, 2017 - frontiersin.org
In this short review, we want to summarize the current findings on the role of vitamin-D in
multiple sclerosis (MS), schizophrenia, and autism. Many studies have highlighted …

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model

J Zhang, S An, W Hu, M Teng, X Wang, Y Qu… - International journal of …, 2016 - mdpi.com
Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological
activities in the prevention of dementia in conditions such as Parkinson's and Alzheimer's …

Autophagy in inflammation, infection, neurodegeneration and cancer

DS Arroyo, EA Gaviglio, JMP Ramos, C Bussi… - International …, 2014 - Elsevier
In its classical form, autophagy is an essential, homeostatic process by which cytoplasmic
components are degraded in a double-membrane-bound autophagosome in response to …

Inonotus obliquus polysaccharides protect against Alzheimer's disease by regulating Nrf2 signaling and exerting antioxidative and antiapoptotic effects

Y Han, S Nan, J Fan, Q Chen, Y Zhang - International Journal of Biological …, 2019 - Elsevier
Inonotus obliquus polysaccharide (IOPS) was initially separated and purified via
precipitation from an aqueous extract with 80% alcohol, a DEAE-52 cellulose anion …

Autophagy down regulates pro-inflammatory mediators in BV2 microglial cells and rescues both LPS and alpha-synuclein induced neuronal cell death

C Bussi, JM Peralta Ramos, DS Arroyo, EA Gaviglio… - Scientific reports, 2017 - nature.com
Autophagy is a fundamental cellular homeostatic mechanism, whereby cells autodigest
parts of their cytoplasm for removal or turnover. Neurodegenerative disorders are associated …

Walnut (Juglans regia) Peptides Reverse Sleep Deprivation-Induced Memory Impairment in Rat via Alleviating Oxidative Stress

S Wang, G Su, Q Zhang, T Zhao, Y Liu… - Journal of agricultural …, 2018 - ACS Publications
The aim of this study was to determine the neuroprotective effects of walnut protein
hydrolysates (WPH) against memory deficits induced by sleep deprivation (SD) in rat and …

Use of LysoTracker dyes: a flow cytometric study of autophagy

S Chikte, N Panchal, G Warnes - Cytometry Part A, 2014 - Wiley Online Library
The flow cytometric use of LysoTracker dyes was employed to investigate the autophagic
process and to compare this with the upregulation of autophagy marker, the microtubule …

Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy

A Noailles, V Maneu, L Campello, P Lax… - Cell death & …, 2018 - nature.com
Retinal neurodegenerative diseases involve a scenario of inflammation and cell death that
leads to morphological alterations and visual impairment. Non-ocular inflammatory …

[HTML][HTML] Recent advances in cerebral cavernous malformation research

A Padarti, J Zhang - Vessel Plus, 2018 - ncbi.nlm.nih.gov
Cerebral cavernous malformations (CCM) are manifested by microvascular lesions
characterized by leaky endothelial cells with minimal intervening parenchyma …