Inflammation is a cellular response to factors that challenge the homeostasis of cells and
tissues. Cell-associated and soluble pattern-recognition receptors, eg Toll-like receptors …

In reply to internal or external danger stimuli, the body orchestrates an inflammatory
response. The endogenous triggers of this process are the damage-associated molecular …

Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although
extensive strides have been made in the treatments for non-diabetic atherosclerosis and its …

The reaction of reducing carbohydrates with amino compounds described in 1912 by Louis‐
Camille Maillard is responsible for the aroma, taste, and appearance of thermally processed …

Inflammation is associated with many neurodegenerative diseases, including Alzheimer's
disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. In this …

Aims To review the evidence for the molecular and cellular processes that may potentially
link periodontal disease and diabetes. The pathogenic roles of cytokines and metabolic …

The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …

Microglia are critical nervous system-specific cells influencing brain development,
maintenance of the neural environment, response to injury, and repair. They contribute to …

ABSTRACT RAGE is a key molecule in the onset and sustainment of the inflammatory
response. New studies indicate that RAGE might represent a new link between the innate …

Diets are currently characterized by elevated sugar intake, mainly due to the increased
consumption of processed sweetened foods and drinks during the last 40 years. Diet is the …