Memory T cells constitute the most abundant lymphocyte population in the body for the
majority of a person's lifetime; however, our understanding of memory T cell generation …

The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells
cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr. 1 Four years later, in …

EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

All humans become infected with multiple herpesviruses during childhood. After clearance
of acute infection, herpesviruses enter a dormant state known as latency. Latency persists …

Abstract In vitro, Epstein-Barr virus (EBV) will infect any resting B cell, driving it out of the
resting state to become an activated proliferating lymphoblast. Paradoxically, EBV persists in …

Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes
by HBV-specific CD8 cells has been assumed to be the central mechanism causing both …

Autoimmune and inflammatory uveitis are a group of potentially blinding intraocular
inflammatory diseases that arise without a known infectious trigger and are often associated …

The deterioration in immune function with aging is thought to make a major contribution to
the increased morbidity and mortality from infectious disease in old age. One aspect of …

To explore the human T cell response to acute viral infection, we performed a longitudinal
analysis of CD8+ T cells responding to the live yellow fever virus and smallpox vaccines …

ContextEpidemiological studies suggest an association between infection with Epstein-Barr
virus (EBV) and risk of multiple sclerosis (MS). ObjectiveTo determine whether elevation in …