Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …

Neutrophil Extracellular Traps (NETs) are a key form of pro-inflammatory cell death of
neutrophils characterized by the extrusion of extracellular webs of DNA containing …

Small cell lung cancer (SCLC) is a recalcitrant, relatively immune-cold, and deadly subtype
of lung cancer. SCLC has been viewed as a single or homogenous disease that includes …

Lymph nodes (LNs) are frequently the first sites of metastasis. Currently, the only prognostic
LN assessment is determining metastatic status. However, there is evidence suggesting that …

Pancreatic cancer (PC) has a poor prognosis, and current therapeutic strategies are
ineffective in advanced diseases. We and others have shown the aberrant expression of …

Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Background Intervertebral disc degeneration (IVDD) is the primary etiology of low back pain
and radicular pain. Recent studies have found that chemokines play a role in IVDD, but the …

Background The formation of secondary organic aerosols (SOA) by atmospheric oxidation
reactions substantially contributes to the burden of fine particulate matter (PM2. 5), which …

Therapy resistance is a significant concern while treating malignant disease. Accumulating
evidence suggests that a subset of cancer cells potentiates tumor survival, therapy …

The complexity of the tumor microenvironment poses significant challenges in cancer
therapy. Here, to comprehensively investigate the tumor-normal ecosystems, we perform an …