Fundamentals and developments in fluorescence-guided cancer surgery
JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …
past decade as a promising and effective method of intraoperative cancer detection. An …
Latest developments in molecular tracers for fluorescence image-guided cancer surgery
Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …
RGD-binding integrins revisited: how recently discovered functions and novel synthetic ligands (re-) shape an ever-evolving field
Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …
investigated as therapeutic targets over the last decades, motivated by their multiple …
High-precision tumor resection down to few-cell level guided by NIR-IIb molecular fluorescence imaging
In vivo fluorescence/luminescence imaging in the near-infrared-IIb (NIR-IIb, 1,500 to 1,700
nm) window under< 1,000 nm excitation can afford subcentimeter imaging depth without any …
nm) window under< 1,000 nm excitation can afford subcentimeter imaging depth without any …
Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making
P Debie, S Hernot - Frontiers in Pharmacology, 2019 - frontiersin.org
Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …
Cyanine conjugate‐based biomedical imaging probes
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …
motivated numerous researchers to explore its imaging capabilities by miscellaneous …
Protein scaffolds: antibody alternatives for cancer diagnosis and therapy
R Luo, H Liu, Z Cheng - RSC chemical biology, 2022 - pubs.rsc.org
Although antibodies are well developed and widely used in cancer therapy and diagnostic
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …
Intraoperative near-infrared imaging can identify neoplasms and aid in real-time margin assessment during pancreatic resection
AD Newton, JD Predina, MH Shin… - Annals of …, 2019 - journals.lww.com
Objective: To determine if intraoperative near-infrared (NIR) imaging carries benefit in
resection of pancreatic neoplasms. Background: Resection of pancreatic malignancies is …
resection of pancreatic neoplasms. Background: Resection of pancreatic malignancies is …
Quicker, deeper and stronger imaging: A review of tumor-targeted, near-infrared fluorescent dyes for fluorescence guided surgery in the preclinical and clinical stages
J Jiao, J Zhang, F Yang, W Song, D Han, W Wen… - European Journal of …, 2020 - Elsevier
Cancer is a public health problem and the main cause of human mortality and morbidity
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …
worldwide. Complete removal of tumors and metastatic lymph nodes in surgery is …
Exploiting molecular probes to perform near‐infrared fluorescence‐guided surgery
Near‐infrared (NIR) fluorescence imaging can provide real‐time navigation for surgeons to
discriminate boundaries between lesions and healthy tissue, which serves as a promising …
discriminate boundaries between lesions and healthy tissue, which serves as a promising …