Our understanding of endocytosis has evolved remarkably in little more than a decade. This
is the result not only of advances in our knowledge of its molecular and biological workings …

The origin and early evolution of eukaryotes in the light of phylogenomics | Genome Biology
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Histone modifications are a crucial source of epigenetic control. SAGA (Spt–Ada–Gcn5
acetyltransferase) is a chromatin‐modifying complex that contains two distinct enzymatic …

In ubiquitin conjugation, different combinations of E2 and E3 enzymes catalyse either
monoubiquitination or ubiquitin chain formation. The E2/E3 complex Rad6/Rad18 …

Biological signalling networks allow living organisms to issue an integrated response to
current conditions and make limited predictions about future environmental changes. Small …

RNA is targeted in biological conflicts by enzymatic toxins or effectors. A vast diversity of
systems which repair or 'heal'this damage has only recently become apparent. Here, we …

Protein ubiquitination is a fundamental regulatory component in eukaryotic cell biology,
where a cascade of ubiquitin activating (E1), conjugating (E2), and ligating (E3) enzymes …

Our understanding of the pervasive involvement of small RNAs in regulating diverse
biological processes has been greatly augmented by recent application of deep …

Aims: Ubiquitin is a highly conserved protein modifier that heavily accumulates during the
oxidative stress response. Here, we investigated the role of the ubiquitination system …

Comparative genomics has become an indispensable part of modern biology due to the
advancements in high‐throughput sequencing technologies and the accumulation of …