[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

R Divella, R De Luca, I Abbate, E Naglieri… - Journal of …, 2016 - ncbi.nlm.nih.gov
Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …

Obesity and cancer mechanisms: cancer metabolism

BD Hopkins, MD Goncalves, LC Cantley - Journal of clinical oncology, 2016 - ascopubs.org
Obesity is a risk factor for cancer development and is associated with poor prognosis in
multiple tumor types. The positive energy balance linked with obesity induces a variety of …

Molecular mechanisms of cancer development in obesity

MJ Khandekar, P Cohen, BM Spiegelman - Nature Reviews Cancer, 2011 - nature.com
The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

H Tilg, AR Moschen - Nature reviews immunology, 2006 - nature.com
There has been much effort recently to define the role of adipocytokines, which are soluble
mediators derived mainly from adipocytes (fat cells), in the interaction between adipose …

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

T Kadowaki, T Yamauchi, N Kubota… - The Journal of …, 2006 - Am Soc Clin Investig
Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue
and directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of …

Obesity and prostate cancer: A narrative review

RL Wilson, DR Taaffe, RU Newton, NH Hart… - Critical Reviews in …, 2022 - Elsevier
Overweight and obese men with prostate cancer are at an increased risk of disease
recurrence, exacerbated treatment-related adverse effects, development of obesity-related …

Obesity, type 2 diabetes, and cancer: the insulin and IGF connection

DH Cohen, D LeRoith - Endocrine-related cancer, 2012 - erc.bioscientifica.com
Epidemiological studies suggest a positive association between obesity and type 2 diabetes
mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance …

The fat side of prostate cancer

G Zadra, C Photopoulos, M Loda - … et Biophysica Acta (BBA)-Molecular and …, 2013 - Elsevier
Prostate cancer (PCa) metabolism appears to be unique in comparison with other types of
solid cancers. Normal prostate cells mainly rely on glucose oxidation to provide precursors …

Obesity and cancer: local and systemic mechanisms

NM Iyengar, CA Hudis… - Annual review of …, 2015 - annualreviews.org
Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …