[HTML][HTML] “Bet hedging” against climate change in developing and adult animals: roles for stochastic gene expression, phenotypic plasticity, epigenetic inheritance and …

WW Burggren, JF Mendez-Sanchez - Frontiers in Physiology, 2023 - frontiersin.org
Animals from embryos to adults experiencing stress from climate change have numerous
mechanisms available for enhancing their long-term survival. In this review we consider …

Unravelling the factors of evolutionary repeatability: insights and perspectives on predictability in evolutionary biology

SM Pearless, NE Freed - Frontiers in Ecology and Evolution, 2024 - frontiersin.org
Evolutionary biology was previously considered a historical science with predictions about
evolutionary trajectories believed to be near impossible. The development of high …

[HTML][HTML] Mutation and selection induce correlations between selection coefficients and mutation rates

BL Gitschlag, AV Cano, JL Payne… - The American …, 2023 - journals.uchicago.edu
The joint distribution of selection coefficients and mutation rates is a key determinant of the
genetic architecture of molecular adaptation. Three different distributions are of immediate …

AadT, a new weapon in Acinetobacter's fight against antibiotics

V Naidu, B Shah, C Maher, IT Paulsen… - …, 2023 - microbiologyresearch.org
Genes encoding a novel multidrug efflux pump, AadT, from the Drug: H+ antiporter 2 family,
were discovered in Acinetobacter multidrug resistance plasmids. Here, we profiled the …

[HTML][HTML] Bias in the arrival of variation can dominate over natural selection in Richard Dawkins's biomorphs

NS Martin, CQ Camargo, AA Louis - PLOS Computational Biology, 2024 - journals.plos.org
Biomorphs, Richard Dawkins's iconic model of morphological evolution, are traditionally
used to demonstrate the power of natural selection to generate biological order from random …

Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity

S Hsiao, S Chen, Y Jiang, Q Wang, Y Yang… - Advanced …, 2024 - Wiley Online Library
The current‐generation adenine base editor (ABE) ABE8e, which has evolved from the
prokaryotic evolution system, exhibits high efficiency in mediating A‐to‐G conversion and is …

Distribution of mutation rates challenges evolutionary predictability

TA Sun, PA Lind - Microbiology, 2023 - microbiologyresearch.org
Natural selection is commonly assumed to act on extensive standing genetic variation. Yet,
accumulating evidence highlights the role of mutational processes creating this genetic …

Are mutations random?

G Monroe - 2023 - academic.oup.com
The idea that “mutations are random” is ubiquitous in evolutionary biology. But do
evolutionary biologists agree on what it means? What does a historical account teach us …

A positive selection at binding site 501 in the B. 1 lineage might have triggered the highly infectious sub-lineages of SARS-CoV-2

BK Tiwary - Gene, 2024 - Elsevier
The descendants of the B lineage are the most predominant variants among the SARS-CoV-
2 virus due to the incorporation of new mutations augmenting the infectivity of the virus …

[HTML][HTML] Assessing the predictability of fungicide resistance evolution through in vitro selection

NJ Hawkins - Journal of Plant Diseases and Protection, 2024 - Springer
Plant pathogens are highly adaptable, and have evolved to overcome control measures
including multiple classes of fungicides. More effective management requires a thorough …