Background: Ferroptosis is a newly proposed form of programmed cell death, and
accumulating evidence suggests that it plays an essential role in the development of …

Iron participates in myriad processes necessary to sustain life. During the past decades,
great efforts have been made to understand iron regulation and function in health and …

Ferroptosis is a new form of regulated cell death resulting from the accumulation of lipid-
reactive oxygen species. A growing number of studies indicate ferroptosis as an important …

Recurrent breast cancer presents significant challenges with aggressive phenotypes and
treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report …

Background Ovarian cancer is a gynaecological tumour has high incidence and mortality
rates. Agrimonolide, isolated from Agrimonia pilosa Ledeb, has multiple biomedical …

Objective The aim was to assess the expression levels of SLC7A11 and GPX4 in relation to
platinum resistance and prognosis in patients with epithelial ovarian cancer (EOC). Design …

All organisms exposed to metabolic and environmental stresses have developed various
stress adaptive strategies to maintain homeostasis. The main bacterial stress survival …

Epithelial ovarian cancer (EOC) accounts for approximately 90% of all ovarian cancer cases
and is the most common cause of gynecological cancer death. Understanding the molecular …

Thymosin β4 (Tβ4) was extracted forty years agofrom calf thymus. Since then, it has been
identified as a G-actin binding protein involved in blood clotting, tissue regeneration …

Cancer cells adapt to environmental changes and alter their metabolic pathways to promote
survival and proliferation. Metabolic reprogramming not only allows tumor cells to maintain a …