This review summarizes the advancements in rhodium-catalyzed asymmetric C–H
functionalization reactions during the last two decades. Parallel to the rapidly developed …

The development of new methods for the direct functionalization of unactivated C–H bonds
is ushering in a paradigm shift in the field of retrosynthetic analysis. In particular, the catalytic …

Inspired by the need for green and sustainable chemistry,(1) synthetic chemists seek more
efficient ways to construct carbon− carbon (C− C) bonds, the essential link in all organic …

A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote
methylene C–H bond amidation of unactivated alkenes. Due to the preference for five …

Conspectus Alkenes are versatile compounds that are readily available on a large scale
from industry or through organic synthesis. The widespread occurrence of alkenes provides …

The synthesis of chiral ketones has been a long focus of chemistry research.
Enantioselective radical hydroacylation, as a useful strategy to access various chiral …

Cobalt–chiral diphoshine catalytic systems promote intramolecular hydroacylation reactions
of 2-acylbenzaldehydes and 2-alkenylbenzaldehydes to afford phthalide and indanone …

A Ni-catalyzed carboxylation of unactivated primary alkyl bromides and sulfonates with CO2
at atmospheric pressure is described. The method is characterized by its mild conditions and …

Intermolecular rhodium catalyzed hydroacylation in the absence of chelation assistance
remains a largely unmet challenge due to competing decarbonylation of the acylrhodium …

Transition metal catalyzed asymmetric reaction is a hot issue and a frontier of the research in
current organic chemistry. The design and synthesis of new type of efficient chiral ligands …