Purine metabolism dysfunctions: experimental methods of detection and diagnostic potential
AFG Cicero, F Fogacci, V Di Micoli, C Angeloni… - International Journal of …, 2023 - mdpi.com
Purines, such as adenine and guanine, perform several important functions in the cell. They
are found in nucleic acids; are structural components of some coenzymes, including NADH …
are found in nucleic acids; are structural components of some coenzymes, including NADH …
The results of the URRAH (Uric acid right for heart health) project: A focus on hyperuricemia in relation to cardiovascular and kidney disease and its role in metabolic …
A Maloberti, A Mengozzi, E Russo, AFG Cicero… - High Blood Pressure & …, 2023 - Springer
Abstract The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases
has already been extensively evaluated, and it was found to be an independent predictor of …
has already been extensively evaluated, and it was found to be an independent predictor of …
Triglyceride-glucose index and mortality in a large Regional-based Italian database (Urrah Project)
L D'Elia, M Masulli, A Virdis, E Casiglia… - The Journal of …, 2025 - academic.oup.com
Purpose Recently, a novel index [the triglyceride-glucose (TyG) index]) was considered a
surrogate marker of insulin resistance (IR); in addition, it was estimated to be a better …
surrogate marker of insulin resistance (IR); in addition, it was estimated to be a better …
Expert consensus for the diagnosis and treatment of patient with hyperuricemia and high cardiovascular risk: 2021 update
C Borghi, J Domienik-Karłowicz, A Tykarski… - Cardiology …, 2021 - journals.viamedica.pl
Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …
[HTML][HTML] Serum uric acid/serum creatinine ratio as a predictor of cardiovascular events. Detection of prognostic cardiovascular cut-off values
Objective: In the frame of the Uric Acid Right for Heart Health (URRAH) study, a nationwide
multicenter study involving adult participants recruited on a regional community basis from …
multicenter study involving adult participants recruited on a regional community basis from …
Serum uric acid predicts all-cause and cardiovascular mortality independently of hypertriglyceridemia in cardiometabolic patients without established CV disease: a …
High serum uric acid (SUA) and triglyceride (TG) levels might promote high-cardiovascular
risk phenotypes across the cardiometabolic spectrum. However, SUA predictive power in the …
risk phenotypes across the cardiometabolic spectrum. However, SUA predictive power in the …
Insulin resistance surrogate markers and risk of hyperuricemia among patients with and without coronary artery disease: A cross-sectional study
Z Ghorbani, SN Mirmohammadali… - Frontiers in …, 2023 - frontiersin.org
Background Although emerging evidence emphasizes the associations between both
insulin resistance and hyperuricemia with coronary artery disease (CAD) risk, no definite …
insulin resistance and hyperuricemia with coronary artery disease (CAD) risk, no definite …
The paradoxical relation between serum uric acid and outcomes of hip fracture in older patients after surgery: A 1-year follow-up study
M Liu, Q Chu, C Yang, J Wang, M Fu, Z Zhang, G Sun - Surgery, 2022 - Elsevier
Background The relation between serum uric acid and bone metabolism has been reported
in many studies, but few studies have focused on serum uric acid and fracture rehabilitation …
in many studies, but few studies have focused on serum uric acid and fracture rehabilitation …
Serum uric acid levels are associated with the echogenic features of carotid plaque vulnerability in elderly patients with atherosclerotic disease
Uric acid is a marker of inflammation and a risk factor for atherosclerosis that has been
suggested to play a role in carotid plaque instability. Reduced atherosclerotic plaque …
suggested to play a role in carotid plaque instability. Reduced atherosclerotic plaque …
Plasma and Urinary Metabolomic Analysis of Gout and Asymptomatic Hyperuricemia and Profiling of Potential Biomarkers: A Pilot Study
Y Ohashi, H Ooyama, H Makinoshima, T Takada… - Biomedicines, 2024 - mdpi.com
Gout results from monosodium urate deposition caused by hyperuricemia, but most
individuals with hyperuricemia remain asymptomatic. The pathogenesis of gout remains …
individuals with hyperuricemia remain asymptomatic. The pathogenesis of gout remains …