Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …

The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …

Oxidative stress-mediated retinal pigment epithelium (RPE) degeneration plays a vital role
in retinal degeneration with irreversible visual impairment, most notably in age-related …

Oxidative stress plays a critical role in age‐related macular degeneration (AMD), and
epithelial‐mesenchymal transition (EMT) is involved in this process. The aim of this study …

In this study, we investigated the preventive effect of Lycium barbarum L. berry extract on
age-related macular degeneration (AMD) and the main components responsible for its …

Dimethyl fumarate (DMF) is a well-known activator of Nrf2 (NF-E2-related factor 2), used in
the treatment of psoriasis and multiple sclerosis. The mechanism of action consists in the …

Scope Age‐related increases in retinal iron are involved in the development of retinal
degeneration. The recently discovered iron‐dependent mechanism of cell death known as …

Thymoquinone is a naturally occurring compound and is the major component of Nigella
sativa, also known as black seed or black cumin. For centuries thymoquinone has been …

Dimethyl fumarate (DMF) is a small molecule currently approved and used in the treatment
of psoriasis and multiple sclerosis due to its immuno-modulatory, anti-inflammatory, and …

Age-related macular degeneration (AMD) is a prevalent degenerative disorder of the central
retina, which holds global significance as the fourth leading cause of blindness. The …