BACKGROUND: Preventive analgesia using non-opioid analgesic strategies is recognized
as a pathway to improve postoperative pain control while minimizing opioid-related side …

One of the most promising pharmaceutical research areas is developing advanced delivery
systems for controlled and sustained drug release. The drug delivery system (DDS) can be …

This study was aimed at preparing, characterising and evaluating in situ gel formulations
based on a blend of two hydrophilic polymers ie poloxamer 407 (P407) and poloxamer 188 …

An organogel, a viscoelastic system, can be regarded as a semi-solid preparation which has
an immobilized external apolar phase. The apolar phase is immobilized within spaces of the …

Opioids have long been used for analgesic purposes for a wide range of procedures.
However, the binding of these drugs to opiate receptors has created various challenges to …

This study investigates pH-sensitive hydrogels based on biocompatible, biodegradable
polysaccharides and natural polymers such as chondroitin sulfate and alginate in …

The aim of this work was to formulate chitosan (CS)-based nanoparticles (NPs) loaded with
ketorolac tromethamine (KT) intended for topical ocular delivery. NPs were prepared using …

Topical ocular delivery of therapeutics are always a challenging arena in order to achieve
high ocular bioavailability with safe administration. Ideal ocular delivery of drug required 4 …

Objective The objective of this study is to investigate the impact of ketorolac and other
nonsteroidal anti-inflammatory drugs on anastomotic leakage after surgery for gastro …

Résumé Objectif Nous avons mene une etude retrospective ala suite de preoccupations
concernant l'augmentation suspectee des besoins de nouvelle exploration chirurgicale pour …