The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …

Preeclampsia: A renal perspective. Preeclampsia is a syndrome that affects 5% of all
pregnancies, producing substantial maternal and perinatal morbidity and mortality. The aim …

This presentation of the diseases of the placenta differs in many ways from the first such
treatment in these volumes by the eminent Robert Meyer. It is a deliberate attempt to bring …

This report updates the 1990 “National High Blood Pressure Education Program Working
Group Report on High Blood Pressure in Pregnancy” and focuses on classification …

The authors explore the hypothesis that tumor necrosis factor‐α (TNF‐α) and possibly other
inflammatory cytokines are overproduced by the placenta in response to local …

Normal pregnancy is associated with reductions in total vascular resistance and arterial
pressure possibly due to enhanced endothelium-dependent vascular relaxation and …

In this systematic review of the existing evidence regarding the relationship between
cigarette smoking during pregnancy and preeclampsia, studies were found through …

Thromboxane A2 (TxA2) causes contraction of vascular smooth muscle and aggregation of
platelets; paradoxically, it also induces formation of the vasodilator and antiaggregant …

Preeclampsia is a multisystem disorder peculiar to human pregnancy. It occurs in 4–5% of
all pregnancies and remains a leading cause of maternal and neonatal mortality and …

Nitric oxide (NO) is a major paracrine mediator and important regulatory agent in various
female reproductive processes, such as ovulation, implantation, pregnancy maintenance …