The use and misuse of antibiotics have made antibiotic-resistant bacteria widespread
nowadays, constituting one of the most relevant challenges for human health at present …

Pseudomonas aeruginosa, able to survive on the surfaces of medical devices, is a life-
threatening pathogen that mainly leads to nosocomial infection especially in …

The epidemiology of antimicrobial resistance (AMR) is complex, with multiple interfaces
(human-animal-environment). In this context, One Health surveillance is essential for …

Fluoroquinolone resistance and the associated genetic mechanisms were assessed by
antimicrobial susceptibility and whole genome sequencing in 56 Pseudomonas aeruginosa …

Fluoroquinolones are widely used as an empirical therapy for pseudomonal ocular
infections. Based on increasing reports on acquired fluoroquinolone resistance genes in …

Enzyme-mediated antibiotic inactivation is a common mechanism of drug resistance in
bacteria (1). The genes encoding these resistance proteins are frequently associated with …

Two novel bla DIM-1-or bla IMP-1-containing genomic islands (GIs) were discovered by
whole-genome sequence analyses in four extensively drug-resistant (XDR) Pseudomonas …

Genomic islands (GEIs) play a vital role in the bacteria's evolutionary adaptation and
pathogenicity. GEIs are the unusual region located in the bacterial genome acquired …

The quinolone resistance crpP genes can mediate decreased susceptibility to quinolones.
However, diversification and prevalence of crpP genes and crpP-carrying integrative and …

Carbapenem-resistant Pseudomonas aeruginosa is a global public health concern. IMP-13
is a carbapenemase that was described for the first time in 2001 but is often underestimated …