Toxicology and pharmacology of synthetic organoselenium compounds: An update

CW Nogueira, NV Barbosa, JBT Rocha - Archives of Toxicology, 2021 - Springer
Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Potentialities of selenium nanoparticles in biomedical science

V Nayak, KRB Singh, AK Singh, RP Singh - New Journal of Chemistry, 2021 - pubs.rsc.org
Nanotechnology is defined as the branch of science dealing with extremely small-sized
particles with a size in the range of 1–100 nm, which are termed nanoparticles. Due to the …

Incorporating selenium into heterocycles and natural products─ from chemical properties to pharmacological activities

W Hou, H Xu - Journal of Medicinal Chemistry, 2022 - ACS Publications
Selenium (Se)-containing compounds have emerged as potential therapeutic agents for the
treatment of a range of diseases. Through tremendous effort, considerable knowledge has …

Selenium compounds as novel potential anticancer agents

D Radomska, R Czarnomysy, D Radomski… - International Journal of …, 2021 - mdpi.com
The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …

Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

CC Konkankit, SC Marker, KM Knopf, JJ Wilson - Dalton Transactions, 2018 - pubs.rsc.org
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Selenium species: current status and potentials in cancer prevention and therapy

HW Tan, HY Mo, ATY Lau, YM Xu - International journal of molecular …, 2018 - mdpi.com
Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

LR Ferguson, H Chen, AR Collins, M Connell… - Seminars in cancer …, 2015 - Elsevier
Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Selenium alleviates cerebral ischemia/reperfusion injury by regulating oxidative stress, mitochondrial fusion and ferroptosis

Y Shi, L Han, X Zhang, L Xie, P Pan, F Chen - Neurochemical research, 2022 - Springer
To clarify the potential role of selenium (Se) on cerebral ischemia/reperfusion (I/R) injury, we
utilized mouse middle cerebral artery occlusion (MCAO) followed by reperfusion as an …

Nanoparticles in cancer diagnosis and treatment

J Baranwal, B Barse, A Di Petrillo, G Gatto, L Pilia… - Materials, 2023 - mdpi.com
The use of tailored medication delivery in cancer treatment has the potential to increase
efficacy while decreasing unfavourable side effects. For researchers looking to improve …

Selenium nanoparticles: Potential in cancer gene and drug delivery

F Maiyo, M Singh - Nanomedicine, 2017 - Taylor & Francis
In recent decades, colloidal selenium nanoparticles have emerged as exceptional selenium
species with reported chemopreventative and therapeutic properties. This has sparked …