The field of ion mobility-mass spectrometry (IM-MS) has grown with significant momentum in
recent years in both fundamental advances and pioneering applications. A search of the …

In this Review, we focus on an important aspect of ion mobility (IM) research, namely, the
reporting of quantitative ion mobility measurements in the form of the gas-phase collision …

In bottom-up proteomics, peptides are separated by liquid chromatography with elution peak
widths in the range of seconds, whereas mass spectra are acquired in about 100 …

Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic
workflows by providing an additional separation dimension as well as a parameter for …

The rapid development of metabolomics has significantly advanced health and disease
related research. However, metabolite identification remains a major analytical challenge for …

The size and shape of peptide ions in the gas phase are an under-explored dimension for
mass spectrometry-based proteomics. To investigate the nature and utility of the peptide …

Unlike traditional drift-tube ion mobility-mass spectrometry, traveling-wave ion mobility-mass
spectrometry typically requires calibration in order to generate collision cross section (CCS) …

Ion mobility mass spectrometry (IM-MS)-derived collision cross section (CCS) values can
serve as a valuable additional identification parameter within the analysis of compounds of …

The enormous dynamic range of proteinaceous species present in protein biotherapeutics
poses a significant challenge for current mass spectrometry (MS)-based methods to detect …

Hybrid analytical instrumentation constructed around mass spectrometry (MS) is becoming
the preferred technique for addressing many grand challenges in science and medicine …