Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Strategies to tune electrospun scaffold porosity for effective cell response in tissue engineering

JM Ameer, AK Pr, N Kasoju - Journal of functional biomaterials, 2019 - mdpi.com
Tissue engineering aims to develop artificial human tissues by culturing cells on a scaffold in
the presence of biochemical cues. Properties of scaffold such as architecture and …

Genetic stability of mesenchymal stromal cells for regenerative medicine applications: a fundamental biosafety aspect

S Neri - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem/stromal cells (MSC) show widespread application for a variety of clinical
conditions; therefore, their use necessitates continuous monitoring of their safety. The risk …

[HTML][HTML] Engineered dual-scale poly (ε-caprolactone) scaffolds using 3D printing and rotational electrospinning for bone tissue regeneration

B Huang, E Aslan, Z Jiang, E Daskalakis, M Jiao… - Additive …, 2020 - Elsevier
Large bone defects due to trauma or disease present a significant clinical challenge with
limited efficacy of current therapies. A key aim is to develop biomimetic scaffolds that reflect …

[HTML][HTML] Cellular modulation by the mechanical cues from biomaterials for tissue engineering

Q Wei, S Wang, F Han, H Wang, W Zhang… - Biomaterials …, 2021 - ncbi.nlm.nih.gov
Mechanical cues from the extracellular matrix (ECM) microenvironment are known to be
significant in modulating the fate of stem cells to guide developmental processes and …

Biodegradable and non-biodegradable biomaterials and their effect on cell differentiation

R Geevarghese, SS Sajjadi, A Hudecki… - International Journal of …, 2022 - mdpi.com
Biomaterials for tissue scaffolds are key components in modern tissue engineering and
regenerative medicine. Targeted reconstructive therapies require a proper choice of …

Challenges in bone tissue regeneration: stem cell therapy, biofunctionality and antimicrobial properties of novel materials and its evolution

O Riester, M Borgolte, R Csuk, HP Deigner - International Journal of …, 2020 - mdpi.com
An aging population leads to increasing demand for sustained quality of life with the aid of
novel implants. Patients expect fast healing and few complications after surgery. Increased …

[HTML][HTML] Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method …

L Burroughs, MH Amer, M Vassey, B Koch… - Biomaterials, 2021 - Elsevier
Human mesenchymal stem cells (hMSCs) are widely represented in regenerative medicine
clinical strategies due to their compatibility with autologous implantation. Effective bone …

Bacterial nanocellulose as novel carrier for intestinal epithelial cells in drug delivery studies

C Fey, J Betz, C Rosenbaum, D Kralisch… - Materials Science and …, 2020 - Elsevier
Synthetic cell carriers (A) represent common scaffold structures for the development of cell-
based in vitro models of the human intestine but due to their low porosity or unwanted …

Polymer microparticles with defined surface chemistry and topography mediate the formation of stem cell aggregates and cardiomyocyte function

M Alvarez-Paino, MH Amer, A Nasir… - … applied materials & …, 2019 - ACS Publications
Surface-functionalized microparticles are relevant to fields spanning engineering and
biomedicine, with uses ranging from cell culture to advanced cell delivery. Varying …