TCGA molecular prognostic groups of endometrial carcinoma: current knowledge and future perspectives

D Arciuolo, A Travaglino, A Raffone… - International journal of …, 2022 - mdpi.com
The four TCGA-based molecular prognostic groups of endometrial carcinoma (EC), ie, POLE-
mutant, mismatch repair (MMR)-deficient, p53-abnormal, and “no specific molecular …

Risk stratification of endometrial cancer patients: FIGO stage, biomarkers and molecular classification

JC Kasius, JMA Pijnenborg, K Lindemann, D Forsse… - Cancers, 2021 - mdpi.com
Simple Summary Endometrial cancer (EC) is the most common gynaecologic malignancy in
developed countries. Most patients are sufficiently treated with removal of uterus, tubes and …

Molecular Regulator Driving Endometriosis Towards Endometrial Cancer: A Multi-Scale Computational Investigation to Repurpose Anti-Cancer drugs

S Mahema, J Roshni, J Raman, SF Ahmad… - Cell Biochemistry and …, 2024 - Springer
Endometriosis is a gynecological disorder among reproductive-aged women. Recent
epidemiological investigations suggest endometriosis increases the risk of endometrial …

Current approaches to the management of patients with endometrial cancer

E Kalampokas, G Giannis, T Kalampokas… - Cancers, 2022 - mdpi.com
Simple Summary New data, the development of new methods of treatment and management
and the rising incidence of endometrial cancer require constant reviewing, in order to inform …

The role of CTNNB1 in endometrial cancer

Ž Ledinek, M Sobočan, J Knez - Disease Markers, 2022 - Wiley Online Library
Endometrial cancer (EC) is the most common gynaecologic malignancy in the developed
countries. Recent evidence suggests that histopathological subtyping together with …

Molecular subtypes of endometrial cancer: Implications for adjuvant treatment strategies

Y Yang, SF Wu, W Bao - International Journal of Gynecology & …, 2024 - Wiley Online Library
Background When determining adjuvant treatment for endometrial cancer, the decision
typically relies on factors such as cancer stage, histologic grade, subtype, and a few …

The metabolomic approach for the screening of endometrial cancer: validation from a large cohort of women scheduled for gynecological surgery

J Troisi, A Mollo, M Lombardi, G Scala, SM Richards… - Biomolecules, 2022 - mdpi.com
Endometrial cancer (EC) is the most common gynecological neoplasm in high-income
countries. Five-year survival rates are related to stage at diagnosis, but currently, no …

Upgrading Treatment and Molecular Diagnosis in Endometrial Cancer—Driving New Tools for Endometrial Preservation?

M Dellino, M Cerbone, AS Laganà, A Vitagliano… - International Journal of …, 2023 - mdpi.com
One emerging problem for onco-gynecologists is the incidence of premenopausal patients
under 40 years of age diagnosed with stage I Endometrial Cancer (EC) who want to …

Clear cell carcinoma of the endometrium

G Bogani, I Ray-Coquard, N Concin, NYL Ngoi… - Gynecologic …, 2022 - Elsevier
Clear cell endometrial carcinoma represents an uncommon and poorly understood entity.
Data from molecular/genomic profiling highlighted the importance of various signatures in …

Integration of histopathological images and multi-dimensional omics analyses predicts molecular features and prognosis in high-grade serous ovarian cancer

H Zeng, L Chen, M Zhang, Y Luo, X Ma - Gynecologic oncology, 2021 - Elsevier
Objective This study used histopathological image features to predict molecular features,
and combined with multi-dimensional omics data to predict overall survival (OS) in high …