Simple Summary B-cell malignancies are a heterogenous group of lymphomas and
leukemias and are the 6th most common cancer-related cause of death. Apart from several …

The IgH intronic enhancer region Eμ is a combination of both a 220-bp core enhancer
element and two 310–350-bp flanking scaffold/matrix attachment regions named MARs Eμ …

We report that the IgH 3′ regulatory region (3′ RR) has no role on μ chain transcription
and pre-BCR expression in B cell progenitors. In contrast, analysis of heterozygous IgH a …

IGH@ proto-oncogene translocation is a common oncogenic event in lymphoid lineage
cancers such as B-ALL, lymphoma and multiple myeloma. Here, to investigate the interplay …

Chromosomal translocations in non-Hodgkin lymphoma (NHL) result in activation of
oncogenes by placing them under the regulation of immunoglobulin heavy chain (IGH) …

Schistosoma japonicum infection showed protective effects against allergic airway
inflammation (AAI). However, controversial findings exist especially regarding the timing of …

B-cell lymphomas and leukemias derive from B cells at various stages of maturation and are
the 6th most common cancer-related cause of death. While the role of several oncogenes …

Much progress has been made in understanding the important cis-mediated controls on
mouse TCRα gene function, including identification of the Eα enhancer and TCRα locus …

Background The naïve antibody repertoire is initially dependent upon the number of
germline V (D) J genes and the ability of recombined heavy and light chains to pair …

Schistosome infection showed protective effects against allergic airway inflammation (AAI).
However, controversial findings exist especially regarding the timing of helminth infection …