Tendinopathy is a multifactorial spectrum of tendon disorders that affects different
anatomical sites and is characterized by activity-related tendon pain. These disorders are …

Background The role of inflammation in tendinopathy has historically been a subject of
significant controversy. Our primary aim was to determine whether inflammatory cell …

Tendon injuries are a common age-related degenerative condition where current treatment
strategies fail to restore functionality and normal quality of life. This disease also occurs …

Improved understanding of the role of inflammation in tendon disease is required to facilitate
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …

Pain and functional limitation are frequent in symptomatic tendinopathy. The essential lesion
of tendinopathy is a failed healing response. Understanding the cellular and molecular …

Aging is associated with an overt inflammatory phenotype and physiological decline.
Specialized proresolving lipid mediators (SPMs) are endogenous autacoids that actively …

Lipids are an essential constituent of the cell membrane of which polyunsaturated fatty acids
(PUFAs) are the most important component. Activation of phospholipase A2 (PLA2) induces …

Background Tendinopathy is common, presents with pain and activity limitation, and is
associated with a high risk of recurrence of the injury. Tendinopathy usually occurs as a …

Injuries to the superficial digital flexor tendon (SDFT) are an important cause of morbidity
and mortality in equine athletes, but the healing response is poorly understood. One …

Simple Summary Lameness due to musculoskeletal disease is the most common diagnosis
in equine veterinary practice. Many of these orthopaedic disorders are chronic problems, for …