Mammalian animal models for dengue virus infection: a recent overview

MEH Kayesh, K Tsukiyama-Kohara - Archives of virology, 2022 - Springer
Dengue, a rapidly spreading mosquito-borne human viral disease caused by dengue virus
(DENV), is a public health concern in tropical and subtropical areas due to its expanding …

Mobilization and activation of the innate immune response to dengue virus

CA King, AD Wegman, TP Endy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Dengue virus is an important human pathogen, infecting an estimated 400 million
individuals per year and causing symptomatic disease in a subset of approximately 100 …

Mouse models of dengue virus infection for vaccine testing

VV Sarathy, GN Milligan, N Bourne, ADT Barrett - Vaccine, 2015 - Elsevier
Dengue is a mosquito-borne disease caused by four serologically and genetically related
viruses termed DENV-1 to DENV-4. With an annual global burden of approximately 390 …

Nanomedicine as a potential novel therapeutic approach against the dengue virus

T Zohra, F Saeed, A Ikram, T Khan, S Alam, M Adil… - …, 2023 - Taylor & Francis
Dengue is an arbovirus infection which is transmitted by Aedes mosquitoes. Its prompt
detection and effective treatment is a global health challenge. Various nanoparticle-based …

Modeling arboviral infection in mice lacking the interferon alpha/beta receptor

A Marín-Lopez, E Calvo-Pinilla, S Moreno… - Viruses, 2019 - mdpi.com
Arboviruses are arthropod-borne viruses that exhibit worldwide distribution and are a
constant threat, not only for public health but also for wildlife, domestic animals, and even …

Non-human primate models of dengue virus infection: a comparison of viremia levels and antibody responses during primary and secondary infection among old …

NA Muhammad Azami, T Takasaki, I Kurane, ML Moi - Pathogens, 2020 - mdpi.com
Due to the global burden of dengue disease, a vaccine is urgently needed. One of the key
points in vaccine development is the development of a robust and reliable animal model of …

A murine model of dengue virus infection in suckling C57BL/6 and BALB/c mice

AB Byrne, AG García, JM Brahamian… - Animal Models and …, 2021 - Wiley Online Library
Dengue is a significant public health concern across tropical and subtropical regions
worldwide, principally causing disease in children. Very young children are at increased risk …

Two cases of natural infection of dengue-2 virus in bats in the Colombian Caribbean

A Calderón, C Guzmán, T Oviedo-Socarras… - Tropical Medicine and …, 2021 - mdpi.com
Dengue, a mosquito-borne zoonotic disease, is the most common vector-borne disease in
tropical and subtropical areas. In this study, we aim to demonstrate biological evidence of …

Development of a transmission model for dengue virus

RC Christofferson, MK McCracken, AM Johnson… - Virology journal, 2013 - Springer
Background Dengue virus (DENV) research has historically been hampered by the lack of a
susceptible vertebrate transmission model. Recently, there has been progress towards such …

Impact of dengue virus (serotype DENV-2) infection on liver of BALB/c mice: A histopathological analysis

S Sakinah, SP Priya, S Kumari, F Amira, K Poorani… - Tissue and Cell, 2017 - Elsevier
In this research, we characterized the histopathological impact of dengue virus (serotype
DENV-2) infection in livers of BALB/c mice. The mice were infected with different doses of …